Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.34 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201321 | 0.84 | BRAF (0.36) | ABCG2ABCB1PDE10AMEN1KMT2A | |
| SCHEMBL22201242 | 0.84 | HTR2C (0.38) | ABCG2ABCB1MEN1KMT2AP2RX3 | |
| SCHEMBL22201239 | 0.83 | PDE5A (0.39) | CSF1RABCG2ABCB1USP2KMT2A | |
| SCHEMBL22201366 | 0.83 | MAPT (0.39) | ABCG2ABCB1MEN1USP2KMT2A | |
| SCHEMBL22201653 | 0.81 | TGFBR1 (0.41) | ABCG2ABCB1P2RX3ADORA3ALDH1A1 | |
| SCHEMBL22201243 | 0.81 | ABCG2 (0.35) | ABCG2ABCB1P2RX3ALDH1A1MAPT | |
| SCHEMBL22201226 | 0.79 | PRKCH (0.37) | PDE10ASYKP2RX3CYP1A2GRM4 | |
| SCHEMBL22201537 | 0.79 | KDM4E (0.42) | PDE10AMEN1KMT2AP2RX3CYP1A2 | |
| SCHEMBL22201586 | 0.79 | PRKCH (0.47) | ABCG2ABCB1MEN1KMT2ASYK | |
| SCHEMBL22201368 | 0.79 | SYK (0.45) | ABCG2ABCB1PDE10AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |