Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 7/20 | 0.35 |
| ▸ | JAK3 | P52333 | 7/20 | 0.35 |
| ▸ | JAK2 | O60674 | 4/20 | 0.35 |
| ▸ | JAK1 | P23458 | 3/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201415 | 0.88 | PIP4K2A (0.37) | KDM4EMEN1KMT2ATYK2JAK3 | |
| SCHEMBL22201239 | 0.87 | PDE5A (0.39) | KMT2ATYK2JAK3JAK2JAK1 | |
| SCHEMBL22201537 | 0.87 | KDM4E (0.42) | KDM4EMEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL22201531 | 0.85 | ABL1 (0.38) | KDM4EMEN1KMT2ATGFBR1ALOX12 | |
| SCHEMBL22201365 | 0.83 | ADORA3 (0.38) | KDM4EMEN1KMT2ATYK2JAK3 | |
| SCHEMBL22201416 | 0.81 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL22201366 | 0.80 | MAPT (0.39) | KDM4EMEN1KMT2AALDH1A1SYK | |
| SCHEMBL22201586 | 0.79 | PRKCH (0.47) | KDM4EMEN1KMT2ATGFBR1ALDH1A1 | |
| SCHEMBL22201489 | 0.79 | SYK (0.37) | KDM4EMEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL22201226 | 0.78 | PRKCH (0.37) | TGFBR1P2RX3PRKD1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |