Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 2/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 3/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201324 | 0.93 | ADORA3 (0.39) | ADORA3P2RX3CSF1REGFRIGF1R | |
| SCHEMBL22201489 | 0.90 | SYK (0.37) | ADORA3P2RX3EGFRPRKCHPRKCE | |
| SCHEMBL22201494 | 0.90 | JAK2 (0.36) | P2RX3PRKCHPRKCEPRKCQPRKCD | |
| SCHEMBL22201531 | 0.88 | ABL1 (0.38) | TGFBR1SYKKDM4EMEN1KMT2A | |
| SCHEMBL22201492 | 0.87 | P2RX3 (0.32) | ADORA3P2RX3PRKCHPRKCETGFBR1 | |
| SCHEMBL22201485 | 0.87 | ULK1 (0.40) | P2RX3KDRLATS1TGFBR1SYK | |
| SCHEMBL22201366 | 0.86 | MAPT (0.39) | EGFRSRCSYKCYP1A2KDM4E | |
| SCHEMBL22201326 | 0.86 | ULK1 (0.40) | ADORA3KDRTGFBR1CYP1A2KDM4E | |
| SCHEMBL22201586 | 0.86 | PRKCH (0.47) | PRKCHPRKCETGFBR1SYKKDM4E | |
| SCHEMBL22201286 | 0.85 | P2RX3 (0.40) | ADORA3P2RX3EGFRIGF1RSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |