Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 9/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201641 | 0.81 | RIPK2 (0.55) | PRKD1SYKTGFBR1PRKCHPRKCE | |
| SCHEMBL22201452 | 0.74 | PRKCH (0.58) | SYKTGFBR1PRKCHPRKCE | |
| SCHEMBL22201469 | 0.73 | FGFR2 (0.62) | PRKD1SYKTGFBR1PRKCHPRKCE | |
| SCHEMBL22201381 | 0.72 | PRKCH (0.51) | SYKTGFBR1PRKCHPRKCEFGFR2 | |
| SCHEMBL22201450 | 0.72 | PRKCH (0.51) | SYKTGFBR1PRKCHPRKCEFGFR2 | |
| SCHEMBL22201638 | 0.71 | KMT2A (0.57) | PRKD1SYKTGFBR1PRKCHPRKCE | |
| SCHEMBL22201449 | 0.70 | PRKCH (0.51) | SYKPRKCHPRKCEFGFR2FLT3 | |
| SCHEMBL22201284 | 0.70 | ABCG2 (0.54) | PRKD1TGFBR1 | |
| SCHEMBL22201470 | 0.69 | PRKCH (0.47) | PRKD1SYKTGFBR1PRKCHPRKCE | |
| SCHEMBL22201369 | 0.67 | LMNA (0.63) | SYKPRKCHPRKCEEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |