SCHEMBL2220368

SCHEMBL2220368

Cc1cc(N2CCCNCCNCCCNCC2)ccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ADRB1 P08588 4/20 0.54
▸ ALDH1A1 P00352 2/20 0.46
▸ USP2 O75604 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ IP6K1 Q92551 1/20 0.46
▸ KDM4E B2RXH2 2/20 0.45
▸ CHRNB2 P17787 6/20 0.42
▸ CHRNA4 P43681 6/20 0.42
▸ MRGPRX4 Q96LA9 1/20 0.42
▸ GLA P06280 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ MCL1 Q07820 1/20 0.41
▸ CHRNA1 P02708 1/20 0.41
▸ CHRNA7 P36544 1/20 0.41
▸ KHK P50053 1/20 0.41
▸ HTR6 P50406 1/20 0.40
▸ HTR7 P34969 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2489674 0.99 ADRB1 (0.52) ADRB1ALDH1A1USP2TSHRHSD17B10
SCHEMBL27107055 0.92 ADRB1 (0.63) ADRB1ALDH1A1USP2TSHRHSD17B10
SCHEMBL2304941 0.83 IP6K1 (0.59) ALDH1A1TSHRHSD17B10IP6K1KDM4E
SCHEMBL30798753 0.79 ADRB1 (0.61) ADRB1ALDH1A1USP2TSHRHSD17B10
SCHEMBL1741562 0.79 ADRB1 (0.61) ADRB1ALDH1A1USP2TSHRHSD17B10
SCHEMBL5231120 0.78 ADRB1 (0.86) ADRB1CHRNB2CHRNA4CHRNA1CHRNA7
SCHEMBL334256 0.77 ALDH1A1 (0.64) ADRB1ALDH1A1USP2TSHRHSD17B10
SCHEMBL15547292 0.77 ADRB1 (0.58) ADRB1ALDH1A1USP2TSHRHSD17B10
SCHEMBL13460161 0.76 IP6K1 (0.49) ADRB1ALDH1A1USP2TSHRHSD17B10
SCHEMBL1336438 0.76 CHEK1 (0.51) IP6K1KDM4EMAPTKMT2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005879-A Modified GRPR antagonist peptides for cancer imaging and treatment 慕尼黑工业大学 2026-05-12 — — CN claimed
US-20260021211-A1 Dual mode radiotracer and -therapeutics UNIV MUENCHEN TECH (DE) 2026-01-22 — — US claimed
EP-4651910-A1 DUAL LABELLED COMPOUNDS TARGETING THE PROSTATE SPECIFIC MEMBRANE ANTIGEN Centre Hospitalier Universitaire Vaudois (CHUV) (CH) 2025-11-26 — — EP claimed
US-12419976-B2 Hybrid tracers for targeted cancer imaging and treatment ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LUMC) GMBH (NL) 2025-09-23 — — US claimed
US-20250288704-A1 CXCR4-LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC USE AND PRECURSORS THEREOF Technische Universität München (DE) 2025-09-18 — — US claimed
US-12390540-B2 Dual mode radiotracer and -therapeutics Technische Universität München (DE) 2025-08-19 — — US claimed
EP-4291250-B1 DUAL MODE RADIOTRACER AND THERAPEUTICS UNIV MUENCHEN TECH (DE) 2025-01-15 — — EP claimed
US-20240399001-A1 RADIOTRACERS AND THERAPEUTICS BINDING TO FIBROBLAST ACTIVATION PROTEIN (FAP) Blue Earth Diagnostics Limited (GB) 2024-12-05 — — US claimed
US-20240366811-A1 RADIONUCLIDE LABELED POLYPEPTIDE CONJUGATES AND USES THEREOF TIANJIN CONJUSTAR BIOLOGICS CO., LTD. (CN) 2024-11-07 — — US claimed
WO-2024222840-A1 NOVEL RADIONUCLIDE-LABELED POLYPEPTIDE CONJUGATE AND USE THEREOF 天津星联肽生物科技有限公司 2024-10-31 — — WO claimed
EP-4043041-A1 CXCR4-LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC USE AND PRECURSORS THEREOF Technische Universität München (DE) 2022-08-17 — — EP claimed
US-20220118120-A1 CANCER DIAGNOSTIC IMAGING AGENTS Technische Universität München (DE) 2022-04-21 — — US claimed
WO-2022018264-A1 SILICON-CONTAINING LIGAND COMPOUNDS Technische Universität München (DE) 2022-01-27 — — WO claimed
EP-3917582-A1 CANCER DIAGNOSTIC IMAGING AGENTS Technische Universität München (DE) 2021-12-08 — — EP claimed
CN-113573743-A Diagnostic imaging agents for cancer 慕尼黑工业大学 2021-10-29 — — CN claimed
WO-2021116712-A1 FUNCTIONALISED MICROBUBBLE MEDIATED CELL TAGGING OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2021-06-17 — — WO claimed
WO-2020157184-A1 CANCER DIAGNOSTIC IMAGING AGENTS Technische Universität München (DE) 2020-08-06 — — WO claimed
US-20200197545-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS TECHNISCHE UNIVERSITÄT MÜNCHEN - KLINIKUM RECHTS DER ISAR (DE) 2020-06-25 — — US claimed
CN-111132700-A Dual-mode radiotracer and therapeutic agent 慕尼黑工业大学 2020-05-08 — — CN claimed
US-20070184537-A1 Method for the linkage of bifunctional chelating agents and (radioactive) transition metal complexes to proteins and peptides PAUL SCHERRER INSTITUT (CH) 2007-08-09 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12419976-B2 Hybrid tracers for targeted cancer imaging and treatment HNRNPF, ANXA3, SLC67A1 ADRB1 878/4885ALDH1A1 2468/4885USP2 3741/4885
US-20240366811-A1 RADIONUCLIDE LABELED POLYPEPTIDE CONJUGATES AND USES THEREOF GRPR, SSTR4, DNPEP ADRB1 3114/4885ALDH1A1 4072/4885USP2 3148/4885
US-20260021211-A1 Dual mode radiotracer and -therapeutics FOLH1, SLC19A1, KLK3 ADRB1 3419/4885ALDH1A1 2663/4885USP2 4302/4885
US-20240399001-A1 RADIOTRACERS AND THERAPEUTICS BINDING TO FIBROBLAST ACTIVATION PROTEIN (FAP) FAP, FIBP, FGFR1 ADRB1 4618/4885ALDH1A1 1672/4885USP2 3557/4885
US-20250288704-A1 CXCR4-LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC USE AND PRECURSORS THEREOF CXCR4, CXCR1, CXCR3 ADRB1 231/4885ALDH1A1 1193/4885USP2 4548/4885
US-20200197545-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS SSTR2, SSTR1, PAICS ADRB1 4453/4885ALDH1A1 3352/4885USP2 4016/4885
US-20070184537-A1 Method for the linkage of bifunctional chelating agents and (radioactive) transition metal complexes to proteins and peptides EPRS1, SLC7A11, QPCTL ADRB1 4859/4885ALDH1A1 4546/4885USP2 1533/4885
US-12390540-B2 Dual mode radiotracer and -therapeutics PAICS, SSTR2, SSTR1 ADRB1 4438/4885ALDH1A1 3163/4885USP2 4166/4885
US-20220118120-A1 CANCER DIAGNOSTIC IMAGING AGENTS FOLH1, FOLR1, KLK3 ADRB1 4410/4885ALDH1A1 1382/4885USP2 4108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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