SCHEMBL2221800

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2221795	1.00	MMP2 (0.50)	MMP2HTTSMN1; SMN2ABCC9KCNJ11
	SCHEMBL3054887	0.82	PDK1 (0.54)	HTTSMN1; SMN2ABCC9KCNJ11MAPT
	SCHEMBL3054885	0.82	PDK1 (0.54)	HTTSMN1; SMN2ABCC9KCNJ11MAPT
	SCHEMBL7936084	0.79	HCRTR2 (0.45)	MMP2SMN1; SMN2MMP3MAPTLMNA
	SCHEMBL3047727	0.79	HCRTR2 (0.45)	MMP2SMN1; SMN2MMP3MAPTLMNA
	SCHEMBL3610994	0.79	MMP2 (0.56)	MMP2HTTABCC9KCNJ11MMP3
	SCHEMBL11196704	0.79	MMP2 (0.56)	MMP2HTTABCC9KCNJ11MMP3
	SCHEMBL11204276	0.78	PDK1 (0.46)	MMP2HTTSMN1; SMN2MMP3MAPT
	SCHEMBL5014650	0.78	MMP2 (0.54)	MMP2HTTABCC9KCNJ11MMP3
	SCHEMBL2220603	0.78	MEN1 (0.45)	MMP2HTTSMN1; SMN2ABCC9KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.