Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175550 | 0.86 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL2223774 | 0.85 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL13121650 | 0.83 | GABRA1 (0.52) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL9408926 | 0.83 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL14324405 | 0.81 | BCL2 (0.41) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL1264757 | 0.80 | GABRA1 (0.51) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL5440579 | 0.80 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL29653496 | 0.80 | DHFR (0.41) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL2146562 | 0.78 | NPC1 (0.67) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL27503559 | 0.78 | ALOX5 (0.43) | NPC1RAB9ALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895754-B2 | Process to make UV radiation absorbing 2-phenyl-1,2,3,-benzotriazoles | DSM IP ASSETS B.V. (NL) | 2014-11-25 | — | — | US | claimed |
| EP-2523943-B1 | PROCESS TO MAKE UV RADIATION ABSORBING 2-PHENYL-1,2,3-BENZOTRIAZOLES | DSM IP ASSETS BV (NL) | 2014-11-19 | — | — | EP | claimed |
| CN-102712605-B | Process to make UV radiation absorbing 2 - phenyl - 1, 2, 3 - benzotriazoles | DSM IP ASSETS BV | 2014-11-12 | — | — | CN | claimed |
| WO-2012163936-A1 | PROCESS FOR THE SYNTHESIS OF BENZOTRIAZOLES USEFUL AS UV-FILTERS | DSM IP ASSETS B.V. (NL) | 2012-12-06 | — | — | WO | claimed |
| US-20120302760-A1 | NOVEL PROCESS | DSM IP ASSETS B.V. (NL) | 2012-11-29 | — | — | US | claimed |
| EP-2523943-A1 | PROCESS TO MAKE UV RADIATION ABSORBING 2 - PHENYL - 1, 2, 3 - BENZOTRIAZOLES | DSM IP Assets B.V. (NL) | 2012-11-21 | — | — | EP | claimed |
| CN-102712605-A | Process to make UV radiation absorbing 2 - phenyl - 1, 2, 3 - benzotriazoles | DSM IP ASSETS BV | 2012-10-03 | — | — | CN | claimed |
| WO-2011086127-A1 | PROCESS TO MAKE UV RADIATION ABSORBING 2 - PHENYL - 1, 2, 3 - BENZOTRIAZOLES | DSM IP ASSETS B.V. (NL) | 2011-07-21 | — | — | WO | claimed |
| US-8895754-B2 | Process to make UV radiation absorbing 2-phenyl-1,2,3,-benzotriazoles | DSM IP ASSETS B.V. (NL) | 2014-11-25 | — | — | US | disclosed |
| US-8895754-B2 | Process to make UV radiation absorbing 2-phenyl-1,2,3,-benzotriazoles | DSM IP ASSETS B.V. (NL) | 2014-11-25 | — | — | US | disclosed |
| US-8895754-B2 | Process to make UV radiation absorbing 2-phenyl-1,2,3,-benzotriazoles | DSM IP ASSETS B.V. (NL) | 2014-11-25 | — | — | US | disclosed |
| EP-2523943-B1 | PROCESS TO MAKE UV RADIATION ABSORBING 2-PHENYL-1,2,3-BENZOTRIAZOLES | DSM IP ASSETS BV (NL) | 2014-11-19 | — | — | EP | disclosed |
| EP-2523943-B1 | PROCESS TO MAKE UV RADIATION ABSORBING 2-PHENYL-1,2,3-BENZOTRIAZOLES | DSM IP ASSETS BV (NL) | 2014-11-19 | — | — | EP | disclosed |
| CN-102712605-B | Process to make UV radiation absorbing 2 - phenyl - 1, 2, 3 - benzotriazoles | DSM IP ASSETS BV | 2014-11-12 | — | — | CN | disclosed |
| US-20120302760-A1 | NOVEL PROCESS | DSM IP ASSETS B.V. (NL) | 2012-11-29 | — | — | US | disclosed |
| US-20120302760-A1 | NOVEL PROCESS | DSM IP ASSETS B.V. (NL) | 2012-11-29 | — | — | US | disclosed |
| EP-2523943-A1 | PROCESS TO MAKE UV RADIATION ABSORBING 2 - PHENYL - 1, 2, 3 - BENZOTRIAZOLES | DSM IP Assets B.V. (NL) | 2012-11-21 | — | — | EP | disclosed |
| CN-102712605-A | Process to make UV radiation absorbing 2 - phenyl - 1, 2, 3 - benzotriazoles | DSM IP ASSETS BV | 2012-10-03 | — | — | CN | disclosed |
| WO-2011086127-A1 | PROCESS TO MAKE UV RADIATION ABSORBING 2 - PHENYL - 1, 2, 3 - BENZOTRIAZOLES | DSM IP ASSETS B.V. (NL) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011086127-A1 | PROCESS TO MAKE UV RADIATION ABSORBING 2 - PHENYL - 1, 2, 3 - BENZOTRIAZOLES | DSM IP ASSETS B.V. (NL) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302760-A1 | NOVEL PROCESS | GABBR1, TPST2, GABBR2 | NPC1 4412/4885RAB9A 4545/4885LMNA 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.