SCHEMBL22222295

SCHEMBL22222295

Clc1ccc2cc(I)n(-c3ccccc3)c2c1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP2 O95551 1/20 0.50
▸ MAT2A P31153 11/20 0.46
▸ MEN1 O00255 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ PRMT5 O14744 2/20 0.43
▸ MAPK8 P45983 1/20 0.40
▸ MAPK9 P45984 1/20 0.40
▸ PLA2G10 O15496 1/20 0.40
▸ PLA2G2A P14555 1/20 0.40
▸ HTR2A P28223 1/20 0.40
▸ HTR2C P28335 1/20 0.40
▸ CYP2A6 P11509 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28365266 0.76 TDP2 (0.47) TDP2MAT2AMEN1LMNAKMT2A
SCHEMBL9423446 0.72 TDP2 (0.50) TDP2MAT2AMEN1LMNAKMT2A
SCHEMBL31339816 0.71 TDP2 (0.51) TDP2MAT2AMEN1LMNAKMT2A
SCHEMBL22103470 0.71 MAT2A (0.58) TDP2MAT2APRMT5CYP1A2
SCHEMBL8899305 0.71 PSMB8 (0.41) MAT2AHTR2AHTR2CCYP2A6
SCHEMBL4928572 0.69 KDM4E (0.50) TDP2MAT2AMEN1LMNAKMT2A
SCHEMBL21452216 0.69 MAT2A (0.52) TDP2MAT2AMEN1LMNAKMT2A
SCHEMBL157573 0.68 BIRC5 (0.62) TDP2MAT2ACYP2A6CYP19A1
SCHEMBL11899480 0.68 L3MBTL1 (0.67) MAT2AMEN1LMNAKMT2AL3MBTL1
SCHEMBL24032391 0.68 MAT2A (0.51) MAT2AMEN1LMNAKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825733-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 — — US disclosed
US-11825733-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 — — US disclosed
US-20200227639-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227639-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, LEF1, KCNC1 TDP2 3280/4885MAT2A 3915/4885MEN1 1712/4885
US-11825733-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SLC25A21, LEF1, KCNC1 TDP2 3280/4885MAT2A 3915/4885MEN1 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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