Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952756 | 0.79 | CA1 (0.46) | NPSR1GAAMAPTALDH1A1MEN1 | |
| SCHEMBL11422092 | 0.75 | POLB (0.42) | NPSR1HTTGAAMAPTALDH1A1 | |
| SCHEMBL10430837 | 0.75 | GABRA1 (0.39) | HDAC3HDAC6 | |
| SCHEMBL6255896 | 0.71 | MAPT (0.39) | HTTMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21787328 | 0.71 | TDP1 (0.46) | ALDH1A1MEN1KMT2ATHRBLMNA | |
| SCHEMBL646260 | 0.70 | TDP1 (0.44) | GAAALDH1A1THRBLMNACYP1A2 | |
| SCHEMBL7809681 | 0.67 | TDP1 (0.46) | NPSR1HTTRAPGEF4GAAMAPT | |
| SCHEMBL14307034 | 0.67 | ERN1 (0.38) | ALDH1A1 | |
| SCHEMBL4632504 | 0.67 | ALDH1A1 (0.46) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22225161 | 0.66 | MMP2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056623-A1 | DENTAL COMPOSITIONS CONTAINING LIQUIDS AND OTHER ELASTOMERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-06-23 | — | — | WO | disclosed |