Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403288 | 0.80 | LMNA (0.49) | LMNAALDH1A1KDM4EHAO2SMN1; SMN2 | |
| SCHEMBL27455057 | 0.79 | LMNA (0.47) | LMNAALDH1A1KDM4EHAO2SMN1; SMN2 | |
| SCHEMBL9615073 | 0.71 | TSHR (0.37) | ENPP2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL27695409 | 0.70 | PTGS2 (0.45) | ENPP2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL525918 | 0.65 | LMNA (0.65) | ENPP2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29990536 | 0.65 | LMNA (0.65) | ENPP2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3171676 | 0.65 | LMNA (0.65) | ENPP2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL447639 | 0.65 | LMNA (0.65) | ENPP2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28146392 | 0.65 | LMNA (0.44) | ENPP2LMNAALDH1A1HSD17B10TSHR | |
| Ammonia Solution, Strong SCHEMBL10589724 | 0.63 | LMNA (0.62) | ENPP2LMNAALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596545-A | Stabilization of zinc oxide films in oral compositions | COLGATE PALMOLIVE CO | 2014-02-19 | — | — | CN | disclosed |
| EP-2654672-A1 | GELATIN ENCAPSULATED ORAL CARE COMPOSITION CONTAINING DENTAL OCCLUSION ACTIVES, HYDROPHOBIC VISCOSITY MODIFIER AND OIL CARRIER | Colgate-Palmolive Company (US) | 2013-10-30 | — | — | EP | disclosed |
| CN-103096979-A | Oral care formulations for malodor control | COLGATE PALMOLIVE CO | 2013-05-08 | — | — | CN | disclosed |
| EP-2512408-A2 | ANTI-EROSION TOOTHPASTE COMPOSITION | Colgate-Palmolive Company (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2012087279-A1 | GELATIN ENCAPSULATED ORAL CARE COMPOSITION CONTAINING DENTAL OCCLUSION ACTIVES, HYDROPHOBIC VISCOSITY MODIFIER AND OIL CARRIER | COLGATE-PALMOLIVE COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2011084673-A2 | ANTI-EROSION TOOTHPASTE COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |
| CN-1191052-C | Dual component dentinal desensitizing dentifrice | COLGATE PALMOLIVE CO (US) | 2005-03-02 | — | — | CN | disclosed |
| CN-1343112-A | Dual component dentinal desensitizing dentifrice | COLGATE PALMOLIVE CO (US) | 2002-04-03 | — | — | CN | disclosed |
| EP-0837670-A1 | ORAL COMPOSITIONS HAVING ACCELERATED TOOTH WHITENING EFFECT | Colgate-Palmolive Company (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997002805-A1 | ORAL COMPOSITIONS HAVING ACCELERATED TOOTH WHITENING EFFECT | COLGATE-PALMOLIVE COMPANY (US) | 1997-01-30 | — | — | WO | disclosed |