Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.61 |
| ▸ | CTSK | P43235 | 9/20 | 0.61 |
| ▸ | CTSB | P07858 | 4/20 | 0.61 |
| ▸ | CTSL | P07711 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236519 | 0.90 | CTSS (0.63) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL3383006 | 0.88 | CTSS (0.77) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL42634 | 0.88 | CTSS (0.62) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL9582823 | 0.88 | CTSS (0.62) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL30968897 | 0.88 | CTSS (0.62) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL13583903 | 0.88 | CTSS (0.62) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL43571 | 0.87 | CA12 (0.70) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL8574599 | 0.87 | CTSS (0.61) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL8574604 | 0.87 | CTSS (0.61) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL7347593 | 0.87 | CTSS (0.61) | CTSSCTSKCTSBCTSLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10716791-B2 | Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof | UNIVERSITY HEALTH NETWORK (CA) | 2020-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10716791-B2 | Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof | PADI2, PADI1, PADI4 | CTSS 1005/4885CTSK 896/4885CTSB 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.