SCHEMBL2222100

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2224726	0.95	SLC6A9 (0.39)	UBE2MDCUN1D1CCR5SLC6A9KCNH2
	SCHEMBL2223642	0.95	UBE2M (0.39)	UBE2MDCUN1D1SLC6A9KCNH2SLC6A5
	SCHEMBL2224442	0.92	CFTR (0.39)	UBE2MDCUN1D1CCR5CHRM5ELANE
	SCHEMBL2222386	0.90	OPRM1 (0.39)	UBE2MDCUN1D1CCR5SLC6A9KCNH2
	SCHEMBL2221367	0.89	THRB (0.41)	UBE2MDCUN1D1CCR5SLC6A9KCNH2
	SCHEMBL2222889	0.88	MAPK1 (0.38)	THRBKMT2ATSHRMEN1ALDH1A1
	SCHEMBL2223311	0.88	ADRB3 (0.37)	UBE2MDCUN1D1CCR5ADRB3ACACB
	SCHEMBL2224947	0.87	CCR5 (0.38)	UBE2MDCUN1D1CCR5ADRB3ACACB
	SCHEMBL15679901	0.87	KDM4E (0.36)	UBE2MDCUN1D1CCR5ADRB3ACACB
	SCHEMBL14649994	0.87	KDM4E (0.36)	UBE2MDCUN1D1ADRB3ACACBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.