Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17929126 | 0.86 | L3MBTL1 (0.50) | THRBTP53RXFP1LMNAMAPT | |
| SCHEMBL680256 | 0.86 | LMNA (0.44) | THRBTP53RXFP1LMNAMAPT | |
| SCHEMBL29812481 | 0.85 | THRB (0.41) | THRBTP53RXFP1LMNAMAPT | |
| SCHEMBL22923944 | 0.82 | MEN1 (0.50) | THRBTP53RXFP1LMNAMAPT | |
| SCHEMBL14975601 | 0.82 | MET (0.43) | THRBTP53RXFP1LMNAMAPT | |
| SCHEMBL23749505 | 0.81 | MET (0.48) | TP53RXFP1LMNAMAPTL3MBTL1 | |
| SCHEMBL680264 | 0.80 | GABRA2 (0.50) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL2592272 | 0.78 | MET (0.51) | MAPTKDM4EMETAXLTYRO3 | |
| SCHEMBL21785863 | 0.77 | TP53 (0.41) | THRBTP53RXFP1LMNAMAPT | |
| SCHEMBL21785957 | 0.72 | ALDH1A1 (0.43) | THRBTP53RXFP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150307-A1 | PHOSPHONATE CONJUGATES AND USES THEREOF | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2020-07-23 | — | — | WO | disclosed |