Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.31 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22254837 | 0.92 | MAPK8 (0.35) | POLBTPSAB1TPSD1TPSG1MAPK8 | |
| SCHEMBL22254871 | 0.88 | TPSAB1 (0.32) | TPSAB1TPSD1TPSG1PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL22233823 | 0.87 | TPSAB1 (0.31) | TPSAB1TPSD1TPSG1PRSS1PRSS2 | |
| SCHEMBL22254148 | 0.86 | USP28 (0.36) | POLBMAPK8USP28USP25 | |
| SCHEMBL22248915 | 0.86 | MAPK8 (0.33) | POLBMAPK8 | |
| SCHEMBL25551709 | 0.84 | POLB (0.33) | POLBMAPK8ROCK2 | |
| SCHEMBL22254135 | 0.84 | POLB (0.33) | POLBMAPK8ROCK2 | |
| SCHEMBL25551386 | 0.83 | POLB (0.38) | POLBTPSAB1TPSD1TPSG1MAPK8 | |
| SCHEMBL22254839 | 0.81 | POLB (0.33) | POLBMAPK8 | |
| SCHEMBL22249124 | 0.80 | ROCK2 (0.36) | POLBROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | POLB 108/4885TPSAB1 2082/4885TPSD1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.