Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154614 | 0.77 | HDAC8 (0.42) | GAAMAPTRXRARXRBALDH1A1 | |
| SCHEMBL93161 | 0.76 | GABRA1 (0.69) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL19998396 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL2154563 | 0.74 | TSHR (0.48) | POLBMAPTALDH1A1HPGDALOX15 | |
| SCHEMBL16694547 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL497733 | 0.74 | CES2 (0.41) | MAPTRXRARXRBRXRGALDH1A1 | |
| SCHEMBL1305213 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL1305235 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL10394690 | 0.73 | GABRA1 (0.65) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL10415675 | 0.73 | GABRA1 (0.65) | GABRA1GABRB2POLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598053-B1 | Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres | OREAL (FR) | 2006-12-20 | — | — | EP | claimed |
| EP-1598053-A1 | Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres | L'OREAL (FR) | 2005-11-23 | — | — | EP | claimed |
| US-20050251928-A1 | Method for stripping artificial color from keratin fibers | L'OREAL (FR) | 2005-11-17 | — | — | US | claimed |
| CN-114426560-B | Chiral diphosphine ligand, rhodium complex thereof, preparation method and application thereof | 南开沧州渤海新区绿色化工研究有限公司 | 2024-11-05 | — | — | CN | disclosed |
| US-20230165771-A1 | PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION | L'OREAL (FR) | 2023-06-01 | — | — | US | disclosed |
| EP-4171490-A1 | PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION | L'OREAL (FR) | 2023-05-03 | — | — | EP | disclosed |
| CN-115996701-A | Method for treating keratin fibres using a high concentration of a specific amino acid | 莱雅公司 | 2023-04-21 | — | — | CN | disclosed |
| WO-2022003040-A1 | PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION | L'OREAL (FR) | 2022-01-06 | — | — | WO | disclosed |
| CN-108774271-A | A kind of chiral nitrogen nitrogen phosphine tridentate ligand and its application based on ferrocene frame having ferrocene frame | 浙江工业大学 | 2018-11-09 | — | — | CN | disclosed |
| WO-2017025244-A1 | COSMETIC PROCESS FOR TREATING KERATIN MATERIALS | L'OREAL (FR) | 2017-02-16 | — | — | WO | disclosed |
| WO-2017018498-A1 | COMPOSITION, PROCESS, METHOD AND USE FOR KERATIN FIBERS | L'OREAL (FR) | 2017-02-02 | — | — | WO | disclosed |
| US-20150166479-A1 | PROCESS FOR SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USED IN SAID PROCESS | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-06-18 | — | — | US | disclosed |
| EP-2876102-A1 | PROCESS FOR SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USED IN SAID PROCESS | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2015-05-27 | — | — | EP | disclosed |
| US-20130224830-A1 | EGGSHELL MEMBRANE SOLUBILIZATION METHOD USING ENZYMES | AMANO ENZYME INC. (JP) | 2013-08-29 | — | — | US | disclosed |
| EP-2612922-A1 | EGGSHELL MEMBRANE SOLUBILIZATION METHOD USING ENZYMES | Amano Enzyme Inc. (JP) | 2013-07-10 | — | — | EP | disclosed |
| WO-2011089985-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2011-07-28 | — | — | WO | disclosed |
| EP-1598053-B1 | Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres | OREAL (FR) | 2006-12-20 | — | — | EP | disclosed |
| EP-1598053-A1 | Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres | L'OREAL (FR) | 2005-11-23 | — | — | EP | disclosed |
| US-20050251928-A1 | Method for stripping artificial color from keratin fibers | L'OREAL (FR) | 2005-11-17 | — | — | US | disclosed |
| US-6084133-A | REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY | KANKYO KAGAKU CENTER CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166479-A1 | PROCESS FOR SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USED IN SAID PROCESS | HMGCR, COASY, APOB | GABRA1 2601/4885GABRB2 2776/4885POLB 699/4885 |
| US-20230165771-A1 | PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION | KRT18, CKAP4, VIM | GABRA1 3720/4885GABRB2 3624/4885POLB 2406/4885 |
| US-20050251928-A1 | Method for stripping artificial color from keratin fibers | KRT18, DSG1, JUP | GABRA1 4394/4885GABRB2 4249/4885POLB 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.