Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22258556 | 0.99 | TRPV1 (0.41) | STAT6TRPV1NTRK1ALDH1A1MEN1 | |
| SCHEMBL22236264 | 0.89 | WNT1 (0.46) | STAT6TRPV1ALDH1A1CYP1A2KCNQ3 | |
| SCHEMBL22235826 | 0.87 | WNT1 (0.46) | STAT6TRPV1ALDH1A1CYP1A2KCNQ3 | |
| SCHEMBL22258547 | 0.84 | LTA4H (0.39) | STAT6ALDH1A1CLK2CLK3DYRK1A | |
| SCHEMBL22258478 | 0.79 | NPC1 (0.41) | TRPV1ALDH1A1KCNQ3KCNQ2WNT1 | |
| SCHEMBL22258230 | 0.78 | NPC1 (0.40) | TRPV1ALDH1A1KCNQ3KCNQ2WNT1 | |
| SCHEMBL22258439 | 0.78 | KCNQ3 (0.41) | TRPV1ALDH1A1CYP1A2KCNQ3KCNQ2 | |
| SCHEMBL22279080 | 0.77 | ALDH1A1 (0.53) | STAT6NTRK1ALDH1A1MEN1CYP1A2 | |
| SCHEMBL22258481 | 0.77 | EGFR (0.55) | STAT6MEN1KMT2AMAPK1RAB9A | |
| SCHEMBL22258549 | 0.76 | LTA4H (0.47) | MEN1HTTKMT2ALTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |