Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965009 | 0.77 | BCHE (0.74) | BCHEACHEALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL8439806 | 0.75 | ALDH1A1 (0.52) | GLAKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11526146 | 0.74 | ALDH1A1 (0.60) | GLAKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6954550 | 0.74 | ACHE (1.00) | BCHEACHEALDH1A1EGFRPKM | |
| SCHEMBL8439121 | 0.73 | ALDH1A1 (0.58) | GLAKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6750273 | 0.73 | ALDH1A1 (0.58) | GLAKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9283647 | 0.72 | ALDH1A1 (0.51) | ACHEGLAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9828159 | 0.72 | HTT (0.58) | GLAKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10924997 | 0.71 | KMT2A (0.68) | GLAKMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9571792 | 0.71 | CA1 (0.51) | ACHEGLAKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3693374-B1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND OR SALT, AND APPLICATION THEREOF | FUJIFILM CORP (JP) | 2022-01-26 | — | — | EP | disclosed |
| US-11208421-B2 | 2-carboxypenam compound or salt thereof, pharmaceutical composition containing novel 2-carboxypenam compound or salt thereof, and applications thereof | FUJIFILM CORPORATION (JP) | 2021-12-28 | — | — | US | disclosed |
| EP-3693374-A1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND OR SALT, AND APPLICATION THEREOF | Fujifilm Corporation (JP) | 2020-08-12 | — | — | EP | disclosed |
| US-20200239495-A1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, AND APPLICATIONS THEREOF | FUJIFILM CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208421-B2 | 2-carboxypenam compound or salt thereof, pharmaceutical composition containing novel 2-carboxypenam compound or salt thereof, and applications thereof | CFTR, SLC11A2, SLC20A1 | BCHE 3658/4885ACHE 4613/4885GLA 1771/4885 |
| US-20200239495-A1 | NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING NOVEL 2-CARBOXYPENAM COMPOUND OR SALT THEREOF, AND APPLICATIONS THEREOF | CFTR, SLC11A2, SLC20A1 | BCHE 3545/4885ACHE 4663/4885GLA 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.