SCHEMBL2226396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2222776	0.94	L3MBTL1 (0.39)	CCR5KDM4EALDH1A1ACACBUBE2M
	SCHEMBL2224441	0.92	NAMPT (0.38)	CCR5KDM4EALDH1A1ACACBOPRK1
	SCHEMBL2222845	0.91	KDM4E (0.39)	CCR5KDM4EMEN1KMT2AUBE2M
	SCHEMBL2221583	0.91	HTR2A (0.38)	ACACBOPRK1
	SCHEMBL2223104	0.91	CCR5 (0.39)	CCR5KDM4EALDH1A1ACACBOPRK1
	SCHEMBL2225596	0.90	SLC1A5 (0.35)	CCR5ALDH1A1ACACBPDE10AUBE2M
	SCHEMBL2221367	0.89	THRB (0.41)	CCR5KDM4EALDH1A1ACACBKMT2A
	SCHEMBL2224420	0.89	HTR2A (0.39)	ACACBKCNH2
	SCHEMBL2223035	0.89	ACACB (0.38)	ACACBOPRK1
	SCHEMBL2223638	0.89	OPRK1 (0.35)	CCR5KDM4EACACBOPRK1PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.