SCHEMBL2222845

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2223015	0.94	FAAH (0.40)	KDM4EUBE2MDCUN1D1FAAH
	SCHEMBL2221367	0.92	THRB (0.41)	KDM4EUBE2MDCUN1D1SLC6A9SLC6A5
	SCHEMBL2226396	0.91	CCR5 (0.40)	KDM4EUBE2MDCUN1D1KCNH2MEN1
	SCHEMBL2223593	0.91	SLC6A9 (0.36)	KDM4EUBE2MDCUN1D1SLC6A9SLC6A5
	SCHEMBL14485091	0.91	KDM4E (0.42)	KDM4ECCR8PTGESSLC6A9SLC6A5
	SCHEMBL2225541	0.88	MAPT (0.46)	KDM4ECCR8PTGESUBE2MDCUN1D1
	SCHEMBL2224167	0.88	MAPT (0.46)	KDM4ECCR8PTGESUBE2MDCUN1D1
	SCHEMBL2222731	0.87	SLC6A2 (0.41)	UBE2MDCUN1D1KCNH2CCR5
	SCHEMBL2222776	0.87	L3MBTL1 (0.39)	KDM4EUBE2MDCUN1D1CCR5
	SCHEMBL2224726	0.86	SLC6A9 (0.39)	KDM4EUBE2MDCUN1D1SLC6A9SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.