SCHEMBL986652

SCHEMBL986652

CCOC=CCc1ccc(C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
RXRA P19793 2/20 0.44
RXRB P28702 2/20 0.44
RARB P10826 7/20 0.42
PLA2G4B P0C869 1/20 0.41
KMT2A Q03164 3/20 0.41
ALDH2 P05091 1/20 0.41
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
RARA P10276 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
MTOR P42345 1/20 0.41
SRD5A2 P31213 2/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
GAA P10253 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10433374 0.78 MAOB (0.56) ALDH1A1KDM4ERECQLTP53TSHR
SCHEMBL10433375 0.78 MAOB (0.56) ALDH1A1KDM4ERECQLTP53TSHR
SCHEMBL28976969 0.77 ALDH1A1 (0.55) ALDH1A1RARBKMT2AALDH2MAPT
SCHEMBL25271314 0.76 XDH (0.47) ALDH1A1RARBPLA2G4BKMT2AMAPT
SCHEMBL12350689 0.76 XDH (0.47) ALDH1A1RARBPLA2G4BKMT2AMAPT
SCHEMBL22273552 0.75 LMNA (0.37) ALDH1A1KMT2APOLBSMN1; SMN2TDP1
SCHEMBL10638128 0.75 LOXL2 (0.56) ALDH1A1KMT2AMAPTMEN1RAB9A
SCHEMBL5805280 0.74 ALDH1A1 (0.52) ALDH1A1RARBKMT2AMAPTPOLB
SCHEMBL5576096 0.74 ALDH1A1 (0.52) ALDH1A1RXRARXRBRARBKMT2A
SCHEMBL9506114 0.74 MAOB (0.62) ALDH1A1POLBSRD5A2NR4A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283424-B2 Process for the synthesis of alpha-olefin polymerization procatalysts RELIANCE INDUSTRIES LIMITED (IN) 2012-10-09 US disclosed
US-20110015355-A1 PROCESS FOR THE SYNTHESIS OF ALPHA-OLEFIN POLYMERIZATION PROCATALYSTS RELIANCE INDUSTRIES LIMITED (IN) 2011-01-20 US disclosed
EP-2257576-A2 A PROCESS FOR THE SYNTHESIS OF ALPHA-OLEFIN POLYMERIZATION PROCATALYSTS Reliance Industries Limited (IN) 2010-12-08 EP disclosed
WO-2009116057-A2 A PROCESS FOR THE SYNTHESIS OF ALPHA-OLEFIN POLYMERIZATION PROCATALYSTS RELIANCE INDUSTRIES LIMITED (IN) 2009-09-24 WO disclosed