SCHEMBL2227704

SCHEMBL2227704

O=C(CCS)OCC(O)CO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
KDM4E B2RXH2 1/20 0.58
DUSP3 P51452 1/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
DGKA P23743 1/20 0.49
FAAH O00519 4/20 0.46
CNR2 P34972 4/20 0.36
ENPP2 Q13822 2/20 0.36
LPAR6 P43657 1/20 0.36
LPAR1 Q92633 1/20 0.36
LPAR4 Q99677 1/20 0.36
LPAR5 Q9H1C0 1/20 0.36
LPAR2 Q9HBW0 1/20 0.36
LPAR3 Q9UBY5 1/20 0.36
MAPT P10636 1/20 0.35
PRKCA P17252 1/20 0.35
PRKCE Q02156 1/20 0.35
PRKCQ Q04759 1/20 0.35
PRKCD Q05655 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996843 0.89 KDM4E (0.44) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL3480022 0.88 KDM4E (0.64) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL236697 0.87 LMNA (0.66) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28888955 0.83 LMNA (0.52) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL107724 0.83 LMNA (0.52) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL839271 0.83 KDM4E (0.72) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL4183885 0.83 KDM4E (0.61) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL270755 0.83 KDM4E (0.79) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL11664025 0.82 KDM4E (0.40) LMNAKDM4EDUSP3MEN1KMT2A
Iodide SCHEMBL10812123 0.81 LMNA (0.50) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12458576-B2 Method for removing color from artificially colored hair L'OREAL (FR) 2025-11-04 US claimed
US-20240122833-A1 METHOD FOR REMOVING COLOR FROM ARTIFICIALLY COLORED HAIR L'OREAL (FR) 2024-04-18 US claimed
EP-3506877-B1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS LABORATOIRE BIOSTHETIQUE KOSMETIK GMBH & CO KG (DE) 2024-03-27 EP claimed
US-20230355496-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS LABORATOIRE BIOSTHETIQUE KOSMETIK GMBH & CO. KG (DE) 2023-11-09 US claimed
EP-3773439-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2021-02-17 EP claimed
US-20210030651-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2021-02-04 US claimed
CN-111936111-A Hair treatment composition comprising a reducing agent 欧莱雅 2020-11-13 CN claimed
WO-2020220098-A1 STABLE HAIR TREATMENT COMPOSITIONS COMPRISING THIOL-BASED REDUCING AGENTS AND CHELATING AGENTS L'OREAL (FR) 2020-11-05 WO claimed
WO-2020061659-A1 STABLE HAIR TREATMENT COMPOSITIONS COMPRISING THIOL-BASED REDUCING AGENTS L'OREAL (FR) 2020-04-02 WO claimed
WO-2019197852-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2019-10-17 WO claimed
WO-2019195900-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2019-10-17 WO claimed
WO-2019195901-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS L'OREAL (FR) 2019-10-17 WO claimed
EP-3506877-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS Laboratoire Biosthetique Kosmetik GmbH&Co. KG (DE) 2019-07-10 EP claimed
US-20190201306-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS LABORATORIE BIOSTHETIQUE KOSMETIK GMBH & CO. KG (DE) 2019-07-04 US claimed
WO-2018042228-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS LABORATOIRE BIOSTHETIQUE KOSMETIK GMBH & CO. KG (DE) 2018-03-08 WO claimed
EP-0405120-B1 COMPOSITION FOR PERMANENT DEFORMATION OF HAIR GOLDWELL AKTIENGESELLSCHAFT (DE) 1993-04-14 EP claimed
US-5068102-A Agent for the long-lasting shaping of hair GOLDWELL AG (DE) 1991-11-26 US claimed
EP-0405120-A2 Composition for permanent deformation of hair GOLDWELL AKTIENGESELLSCHAFT (DE) 1991-01-02 EP claimed
EP-3893834-B1 STRAIGHTENING PROCESS FOR KERATIN FIBERS OREAL (FR) 2026-04-29 EP disclosed
EP-0405120-A2 Composition for permanent deformation of hair GOLDWELL AKTIENGESELLSCHAFT (DE) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458576-B2 Method for removing color from artificially colored hair TYR, COXFA4L2, CAT LMNA 2349/4885KDM4E 810/4885DUSP3 996/4885
US-20210030651-A1 HAIR TREATMENT COMPOSITIONS COMPRISING REDUCING AGENTS TST, DSG1, TYR LMNA 4276/4885KDM4E 931/4885DUSP3 761/4885
US-20230355496-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS KRT18, CUTA, CRYAA LMNA 455/4885KDM4E 2322/4885DUSP3 4705/4885
US-20240122833-A1 METHOD FOR REMOVING COLOR FROM ARTIFICIALLY COLORED HAIR TYR, COXFA4L2, CAT LMNA 2349/4885KDM4E 810/4885DUSP3 996/4885
US-20190201306-A1 CONCENTRATE FOR KERATIN FIBER TREATMENT COMPOSITIONS KRT18, CUTA, CRYAA LMNA 455/4885KDM4E 2322/4885DUSP3 4705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.