SCHEMBL3480022

SCHEMBL3480022

O=C(CCCS)OCC(O)CO

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.64
DUSP3 P51452 1/20 0.64
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
LMNA P02545 1/20 0.64
DGKA P23743 1/20 0.54
FAAH O00519 4/20 0.51
ENPP2 Q13822 2/20 0.41
MAPT P10636 1/20 0.41
LPAR6 P43657 1/20 0.41
LPAR1 Q92633 1/20 0.41
LPAR4 Q99677 1/20 0.41
LPAR5 Q9H1C0 1/20 0.41
LPAR2 Q9HBW0 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41
PRKCA P17252 3/20 0.40
PRKCE Q02156 1/20 0.40
PRKCQ Q04759 1/20 0.40
PRKCD Q05655 1/20 0.40
CNR2 P34972 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2227704 0.88 LMNA (0.58) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL839271 0.88 KDM4E (0.72) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL270755 0.88 KDM4E (0.79) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL839526 0.86 LMNA (0.82) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL380177 0.86 LMNA (0.82) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL8332902 0.86 LMNA (0.82) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL20624 0.86 LMNA (0.82) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL10797197 0.86 LMNA (0.82) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL1840580 0.84 KDM4E (0.68) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL822924 0.84 KDM4E (0.79) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252296-B2 Aqueous polymer dispersion and use thereof in cosmetics BASF SE (DE) 2012-08-28 US disclosed
US-20100204045-A1 Systemicity Enhancers BASF SE (DE) 2010-08-12 US disclosed
EP-2205097-A1 SYSTEMICITY ENHANCERS BASF SE (DE) 2010-07-14 EP disclosed
CN-101631805-A Cationic polymers as thickeners for aqueous and alcoholic compositions BASF AG 2010-01-20 CN disclosed
WO-2009040248-A1 SYSTEMICITY ENHANCERS BASF SE (DE) 2009-04-02 WO disclosed
CN-100412095-C Aqueous polymer dispersions BASF AG (DE) 2008-08-20 CN disclosed
US-20080194708-A1 Cationic Polymers as Thickeners for Aqueous and Alcoholic Compositions BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20080153925-A1 Use of Amphiphilic Copolymers as Solubilising Agents BASF AKTIENGESELLSCHAFT (DE) 2008-06-26 US disclosed
CN-101080426-A Use of amphiphilic copolymers as solubilising agents BASF AG (DE) 2007-11-28 CN disclosed
US-20070197767-A1 Method for producing polymers that are predominantly formed from vinvyl formamide BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US disclosed
US-20060153793-A1 Aqueous polymer dispersion and use thereof in cosmetics BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 US disclosed
CN-1729214-A Aqueous polymer dispersions BASF AG (DE) 2006-02-01 CN disclosed
US-20050265950-A1 Cross-linked cationic copolymers comprising regulators, and use therof in cosmetic preparations for hair BASF AKTIENGESELLSCHAFT (DE) 2005-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194708-A1 Cationic Polymers as Thickeners for Aqueous and Alcoholic Compositions ADH1A, ADH1C, PCNA KDM4E 3521/4885DUSP3 4854/4885MEN1 2117/4885
US-20060153793-A1 Aqueous polymer dispersion and use thereof in cosmetics ALAD, ACMSD, PADI4 KDM4E 2897/4885DUSP3 4388/4885MEN1 2004/4885
US-20080153925-A1 Use of Amphiphilic Copolymers as Solubilising Agents VCL, ASS1, CCNL2 KDM4E 4100/4885DUSP3 4803/4885MEN1 1761/4885
US-20100204045-A1 Systemicity Enhancers C3AR1, C5, CHRM1 KDM4E 1902/4885DUSP3 4430/4885MEN1 616/4885
US-20050265950-A1 Cross-linked cationic copolymers comprising regulators, and use therof in cosmetic preparations for hair ETF1, MTHFD2, TWF2 KDM4E 2998/4885DUSP3 1384/4885MEN1 1927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.