Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20346931 | 0.81 | ATM (0.38) | MAPTALDH1A1HPGDTSHRL3MBTL1 | |
| SCHEMBL25318763 | 0.80 | RAB9A (0.45) | MAPTALDH1A1HPGDL3MBTL1KMT2A | |
| SCHEMBL1393022 | 0.80 | ALDH1A1 (0.39) | MAPTALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL22279545 | 0.79 | HRH3 (0.41) | ALDH1A1HPGDTSHRSIGMAR1KMT2A | |
| SCHEMBL1393185 | 0.77 | SMN1; SMN2 (0.43) | MAPTALDH1A1HPGDTSHRL3MBTL1 | |
| SCHEMBL21570231 | 0.75 | ALDH1A1 (0.37) | MAPTALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL21570233 | 0.72 | SMN1; SMN2 (0.41) | MAPTALDH1A1HPGDTSHRPOLB | |
| SCHEMBL12044892 | 0.70 | NPC1 (0.34) | MAPTALDH1A1POLBSIGMAR1KMT2A | |
| SCHEMBL14704043 | 0.67 | DRD3 (0.39) | MAPTALDH1A1HPGDKMT2AMAPK1 | |
| SCHEMBL4966607 | 0.67 | KMT2A (0.33) | MAPTALDH1A1HPGDTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180472-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2021-11-23 | — | — | US | disclosed |
| US-20200239434-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180472-B2 | Antibacterial compounds | FDPS, SQOR, NDUFS3 | MAPT 1437/4885ALDH1A1 1869/4885HPGD 976/4885 |
| US-20200239434-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | MAPT 1437/4885ALDH1A1 1869/4885HPGD 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.