SCHEMBL2228128

SCHEMBL2228128

CC1(C)OB(c2cc3c4c(cccc4c2)-c2ccccc2-3)OC1(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 11/20 0.49
LIPG Q9Y5X9 11/20 0.49
ALDH1A1 P00352 3/20 0.44
TSHR P16473 3/20 0.44
MAPK1 P28482 3/20 0.44
HSD17B10 Q99714 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
KLK7 P49862 1/20 0.41
CASP1 P29466 3/20 0.40
HPGD P15428 2/20 0.40
HIF1A Q16665 2/20 0.40
CASP7 P55210 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.37
PABPC1 P11940 1/20 0.37
DNMT1 P26358 1/20 0.37
TYMS P04818 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21368178 0.89 LPL (0.40) LPLLIPGALDH1A1TSHRMAPK1
SCHEMBL12729127 0.88 LIPG (0.41) LPLLIPGALDH1A1TSHRMAPK1
SCHEMBL2229145 0.86 LIPG (0.48) LPLLIPGALDH1A1TSHRMAPK1
SCHEMBL12729158 0.85 LIPG (0.40) LPLLIPGALDH1A1TSHRMAPK1
SCHEMBL25908302 0.84 KDM4E (0.53) LPLLIPGMAPK1ATMTYMS
SCHEMBL12729138 0.83 LIPG (0.41) LPLLIPGALDH1A1TSHRMAPK1
SCHEMBL12776642 0.83 LPL (0.38) LPLLIPGALDH1A1TSHRMAPK1
SCHEMBL25221885 0.83 LIPG (0.52) LPLLIPGALDH1A1TSHRMAPK1
SCHEMBL28217 0.81 LIPG (0.56) LPLLIPGALDH1A1TSHRHSD17B10
SCHEMBL21114283 0.81 LIPG (0.40) LPLLIPGALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146296-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-08-03 WO disclosed
EP-3368520-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-04-26 EP disclosed
US-11355714-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-06-07 US disclosed
US-11302870-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2022-04-12 US disclosed
CN-111116489-A Compound, display panel and display device 武汉天马微电子有限公司 2020-05-08 CN disclosed
US-20190288206-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-19 US disclosed
US-20190058133-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-02-21 US disclosed
WO-2017071791-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-05-04 WO disclosed
US-7977869-B2 Organic luminescent device and benzo[k]fluoranthene compound CANON KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20100123390-A1 LIGHT-EMITTING DEVICE, IMAGE DISPLAY APPARATUS, AND NOVEL ORGANIC COMPOUND CANON KABUSHIKI KAISHA (JP) 2010-05-20 US disclosed
US-20100123390-A1 LIGHT-EMITTING DEVICE, IMAGE DISPLAY APPARATUS, AND NOVEL ORGANIC COMPOUND CANON KABUSHIKI KAISHA (JP) 2010-05-20 US disclosed
US-20090278447-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2009-11-12 US disclosed
EP-2049616-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[K]FLUORANTHENE COMPOUND Canon Kabushiki Kaisha (JP) 2009-04-22 EP disclosed
WO-2008015945-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100123390-A1 LIGHT-EMITTING DEVICE, IMAGE DISPLAY APPARATUS, AND NOVEL ORGANIC COMPOUND OCIAD1, OCIAD2, OR51E2 LPL 1190/4885LIPG 1422/4885ALDH1A1 163/4885
US-11302870-B2 Materials for electronic devices EFNA1, PNMT, FLNB LPL 4429/4885LIPG 2616/4885ALDH1A1 365/4885
US-11355714-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2A1, SLCO2B1 LPL 4054/4885LIPG 2734/4885ALDH1A1 1315/4885
US-20090278447-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND FOXK1, KCNK10, F10 LPL 550/4885LIPG 1545/4885ALDH1A1 1170/4885
US-20190058133-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2A1, SLCO2B1 LPL 4054/4885LIPG 2734/4885ALDH1A1 1315/4885
US-20190288206-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, PNMT, FLNB LPL 4415/4885LIPG 2668/4885ALDH1A1 337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.