SCHEMBL22283370

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5604543	0.86	CES2 (0.51)	LMNACYP3A4ALOX15NPC1RAB9A
	SCHEMBL15470537	0.83	LMNA (0.46)	LMNACYP3A4ALOX15NPC1RAB9A
	SCHEMBL22293372	0.81	LMNA (0.47)	LMNACYP3A4ALOX15NPC1RAB9A
	SCHEMBL15470644	0.80	LMNA (0.41)	LMNACYP3A4ALOX15MAPK1CES2
	SCHEMBL25380939	0.78	LMNA (0.59)	LMNACYP3A4ALOX15NPC1RAB9A
	SCHEMBL12663607	0.77	LMNA (0.60)	LMNACYP3A4ALOX15NPC1RAB9A
	SCHEMBL25380943	0.77	LMNA (0.57)	LMNACYP3A4ALOX15NPC1RAB9A
	SCHEMBL22373370	0.76	ELANE (0.50)	ELANECA1CA2NPC1RAB9A
	SCHEMBL3503694	0.74	LMNA (0.44)	LMNACYP3A4ALOX15NPC1RAB9A
	SCHEMBL17389214	0.73	LMNA (0.53)	LMNACYP3A4ALOX15NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.