Fluoride

Fluoride

SCHEMBL22287282

F.O.[SiH4]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Fluoride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL30529880 1.00
Fluoride SCHEMBL27501483 1.00
Fluoride SCHEMBL27951578 1.00
Methane SCHEMBL27489507 0.87
Fluoride SCHEMBL9550138 0.87
Fluoride SCHEMBL27848163 0.87
Fluoride SCHEMBL10825864 0.87
Fluoride SCHEMBL21528063 0.87
Fluoride SCHEMBL19022545 0.87
Fluoride SCHEMBL10825865 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111863927-A Flexible display substrate and flexible display device 京东方科技集团股份有限公司 2020-10-30 CN claimed
CN-107376509-B The preparation method of the superfine modified glass fiber filter material of fluorine silicon oxygen 辽宁凯富环保科技集团有限公司 2019-08-13 CN claimed
CN-110003441-A A kind of preparation method of UV curable water-borne isocyanates grafting fluorosilicone modified epoxy acrylate resin 广州大学 2019-07-12 CN claimed
CN-107090197-B A kind of super-amphiphobic coating and its preparation method and application with formaldehyde degradation by photocatalytic oxidation process function 东南大学 2019-04-30 CN claimed
CN-109441937-A A kind of fiber gasket and preparation method thereof with cross section sealing 成都天府垫片科技有限公司 2019-03-08 CN claimed
CN-109334943-A High-altitude balloon filling device X开发有限责任公司 2019-02-15 CN claimed
CN-109096915-A Coating composition and coating and coating and silica coating and the method for having cated product and forming coating in substrate surface 广东美的厨房电器制造有限公司 2018-12-28 CN claimed
CN-108977919-A A kind of antibacterial far infrared health care rapid-curing cutback nylon fibre and its preparation method and application 太极石股份有限公司 2018-12-11 CN claimed
CN-108795290-A Coating composition and coating and coating and silica coating and the method for having cated product and forming coating in substrate surface 广东美的厨房电器制造有限公司 2018-11-13 CN claimed
CN-108551713-A A kind of Electrostatic Absorption panel 成都同明新材料技术有限公司 2018-09-18 CN claimed
CN-106632968-A Preparation method of fluorosilicone modified waterborne UV cured hyperbranched brush polyurethane 江南大学 2017-05-10 CN claimed
CN-101824151-B Extrusion synthesis method for fluorine-silicon-oxygen polymer body anion ring-opening polymerization reaction UNIV EAST CHINA SCIENCE & TECH 2012-05-30 CN claimed
CN-101824151-A Method for synthesizing fluorine-silicon-oxygen polymer body through anion ring-opening polymerization and reactive extrusion UNIV EAST CHINA SCIENCE & TECH 2010-09-08 CN claimed
CN-117843337-A Low-carbon heat-insulation hydrophobic magnesium oxysulfide cement-biomass fiber foaming material and preparation method thereof 浙江农林大学 2024-04-09 CN disclosed
US-11374038-B2 Array substrate having protection region on same layer as gate insulating layer and manufacturing method thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-06-28 US disclosed
CN-111863927-A Flexible display substrate and flexible display device 京东方科技集团股份有限公司 2020-10-30 CN disclosed
CN-100429009-C Method of forming hydrophobic transparent film on the surface of different substrates SHANGHAI INST CERAMIC CHEM (CN) 2008-10-29 CN disclosed
CN-100410687-C Method for preparing superhard waterproof substances used for spectacle lens WENZHOU LUBAO OPTICS TECHNOLOG (CN) 2008-08-13 CN disclosed
CN-1877368-A Method for preparing superhard waterproof substances used for spectacle lens WENZHOU LUBAO OPTICS TECHNOLOG (CN) 2006-12-13 CN disclosed
CN-1447414-A Mfg. method of semiconductor device with opening portion SANYO ELECTRIC CO (JP) 2003-10-08 CN disclosed