Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 11/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.45 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30519180 | 0.85 | CCNE1 (0.56) | CCNE1CDK2GSK3BMAPK10ALDH1A1 | |
| SCHEMBL3431712 | 0.80 | L3MBTL1 (0.61) | CDK2RIOK2MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL3421180 | 0.79 | SMN1; SMN2 (0.57) | WNT3AMAPK10ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3418702 | 0.76 | CDK2 (0.57) | CCNE1CDK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8566672 | 0.75 | PSEN1 (0.48) | WNT3ARIOK2MAPK10PSEN1PSEN2 | |
| SCHEMBL16126517 | 0.75 | GLS (0.50) | CDK2RIOK2ALDH1A1L3MBTL1MAPK8 | |
| SCHEMBL3423175 | 0.75 | CCNB2 (0.63) | CCNE1CDK2RIOK2MAPK10ALDH1A1 | |
| SCHEMBL3421534 | 0.75 | GLS (0.50) | WNT3ACDK2L3MBTL1MAPK8 | |
| SCHEMBL22286745 | 0.74 | CDK2 (0.60) | CCNE1CDK2GSK3B | |
| SCHEMBL22286713 | 0.74 | CDK2 (0.60) | CCNE1CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157652-A2 | CDK2 INHIBITORS | PFIZER INC. (US) | 2020-08-06 | — | — | WO | disclosed |