Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150178 | 1.00 | GABRA1 (0.38) | GABRA1GABRB2HMGCRCYP2C19CYP1A2 | |
| SCHEMBL2232216 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2HMGCRHTR1DHTR1B | |
| SCHEMBL2149404 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2HMGCRHTR1DHTR1B | |
| SCHEMBL2149504 | 0.80 | DHFR (0.33) | CYP2C19CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL2150025 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2HMGCRCYP2C19CYP1A2 | |
| SCHEMBL2149363 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2HMGCRCYP2C19CYP1A2 | |
| SCHEMBL2149558 | 0.77 | GABRA1 (0.46) | GABRA1GABRB2HMGCRCYP2C19HTR1D | |
| SCHEMBL2149565 | 0.77 | GABRA1 (0.46) | GABRA1GABRB2HMGCRCYP2C19HTR1D | |
| SCHEMBL5872470 | 0.76 | CYP2D6 (0.47) | CYP2C19CYP1A2DPP7KDM4E | |
| SCHEMBL5872314 | 0.76 | CYP2D6 (0.47) | CYP2C19CYP1A2DPP7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680328-B2 | Method for producing optically active cyclopropane carboxylic acid ester compound, asymmetric copper complex, and optically active salicylideneaminoalcohol compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-25 | — | — | US | disclosed |
| US-20110166372-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166372-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND | ALDH18A1, ALDH3A1, DECR1 | GABRA1 346/4885GABRB2 566/4885HMGCR 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.