Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352389 | 0.90 | LMNA (0.57) | LMNAMAPK1CYP2D6CYP2C9HSD17B10 | |
| SCHEMBL7262029 | 0.90 | LMNA (0.57) | LMNAMAPK1CYP2D6CYP2C9HSD17B10 | |
| Mandelic Acid SCHEMBL9747772 | 0.79 | LMNA (0.75) | LMNAMAPK1CYP2D6CYP2C9HSD17B10 | |
| Mandelic Acid SCHEMBL3645 | 0.79 | LMNA (0.75) | LMNAMAPK1CYP2D6CYP2C9HSD17B10 | |
| Mandelic Acid SCHEMBL388417 | 0.78 | LMNA (0.72) | LMNAMAPK1CYP2D6CYP2C9HSD17B10 | |
| SCHEMBL28579226 | 0.74 | LMNA (0.59) | LMNAMAPK1CYP2D6CYP2C9HSD17B10 | |
| Methenamine SCHEMBL204606 | 0.74 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KLK7 | |
| SCHEMBL8475294 | 0.73 | KLK7 (0.48) | ALDH1A1KMT2AKLK7 | |
| SCHEMBL23059830 | 0.73 | ALDH1A1 (0.47) | LMNAMAPK1CYP2D6SRCALDH1A1 | |
| SCHEMBL11508509 | 0.73 | CYP2D6 (0.43) | LMNAMAPK1CYP2D6SMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171195-A1 | METHODS AND COMPOSITIONS FOR TREATING URINARY TRACT INFECTIONS USING AGENTS THAT MIMIC OR ELEVATE CYCLIC AMP | DUKE UNIVERSITY (US) | 2011-07-14 | — | — | US | disclosed |
| US-5171563-A | Cleavable linkers for the reduction of non-target organ retention of immunoconjugates | NEORX CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171195-A1 | METHODS AND COMPOSITIONS FOR TREATING URINARY TRACT INFECTIONS USING AGENTS THAT MIMIC OR ELEVATE CYCLIC AMP | PDE7A, PDE8A, PDE8B | LMNA 859/4885MAPK1 2510/4885CYP2D6 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.