Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262029 | 1.00 | LMNA (0.57) | LMNAMAPK1CES2CES1CYP2D6 | |
| Methenamine SCHEMBL2233803 | 0.90 | LMNA (0.47) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL28579226 | 0.82 | LMNA (0.59) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL8475294 | 0.81 | KLK7 (0.48) | ALDH1A1KMT2AKLK7 | |
| SCHEMBL23059830 | 0.81 | ALDH1A1 (0.47) | LMNAMAPK1CYP2D6SRCALDH1A1 | |
| SCHEMBL11508509 | 0.81 | CYP2D6 (0.43) | LMNAMAPK1CYP2D6SRCALDH1A1 | |
| SCHEMBL5898746 | 0.80 | LMNA (0.56) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL5898749 | 0.80 | LMNA (0.56) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL12134271 | 0.79 | SRC (0.50) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL3711578 | 0.79 | GABBR2 (0.42) | LMNAMAPK1CYP2D6SRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011133436-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2011-10-27 | — | — | WO | claimed |
| US-20110027336-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-02-03 | — | — | US | claimed |
| US-20150054202-A1 | METHOD TO MINIMIZE MOLECULAR WEIGHT DROP OF POLY(L-LACTIDE) STENT DURING PROCESSING | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-02-26 | — | — | US | disclosed |
| US-20120093737-A1 | LIGHT-ABSORBING COMPOSITIONS AND METHODS OF USE | ALLELE BIOTECHNOLOGY AND PHARMACEUTICALS, INC. | 2012-04-19 | — | — | US | disclosed |
| US-8152931-B2 | Dishwasher detergent with excellent rinsing power | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-8148294-B2 | Metal-polymer composites comprising nanostructures and applications thereof | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120076842-A1 | COSMETIC USE OF TYR-ARG DIPEPTIDE TO COMBAT CUTANEOUS SAGGING | SEDERMA (FR) | 2012-03-29 | — | — | US | disclosed |
| US-8123867-B2 | Phosphate-free dishwasher detergent with excellent rinsing power | BASF SE (DE) | 2012-02-28 | — | — | US | disclosed |
| EP-2419076-A2 | COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES | Sederma (FR) | 2012-02-22 | — | — | EP | disclosed |
| US-20120028916-A1 | COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES | SEDERMA (FR) | 2012-02-02 | — | — | US | disclosed |
| US-20120014887-A1 | NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMO-PHARMACEUTICAL USES | SEDERMA (FR) | 2012-01-19 | — | — | US | disclosed |
| US-20110083957-A1 | Continuous Method For Producing Amides Of Aliphatic Hydroxycarboxylic Acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-04-14 | — | — | US | disclosed |
| US-20110065622-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION FOR SEMICONDUCTOR PROCESSING | EKC TECHNOLOGY, INC. | 2011-03-17 | — | — | US | disclosed |
| EP-2046283-B1 | COMPOSITION COMPRISING SARSASAPOGENIN | SEDERMA SA (FR) | 2011-03-16 | — | — | EP | disclosed |
| US-20110045036-A1 | Cosmetic Compositions Comprising at Least One Peptide with at Least One Immobilized Aromatic Cycle | SEDERMA (FR) | 2011-02-24 | — | — | US | disclosed |
| US-20110033507-A1 | Polypeptides KXK and Their Use | SEDERMA (FR) | 2011-02-10 | — | — | US | disclosed |
| US-20110027336-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20110002865-A1 | MOISTURIZING COSMETIC COMPOSITION COMPRISING A COMBINATION OF HOMARINE AND ERYTHRITOL | SEDERMA, S.A.S. (FR) | 2011-01-06 | — | — | US | disclosed |
| US-6653498-B2 | Reacting an aldehyde with hydrogen cyanide in a water immiscible organic solvent and water, using the enzyme (R)-hydroxynitrile lyase | CLARIANT GMBH (DE) | 2003-11-25 | — | — | US | disclosed |
| US-20020052523-A1 | Process for preparing optically active cyanohydrins and secondary products | CLARIANT GMBH | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052523-A1 | Process for preparing optically active cyanohydrins and secondary products | DOHH, OGDH, AOX1 | LMNA 542/4885MAPK1 2827/4885CES2 290/4885 |
| US-20120014887-A1 | NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMO-PHARMACEUTICAL USES | CUTA, PLOD3, MC1R | LMNA 1856/4885MAPK1 1934/4885CES2 4406/4885 |
| US-20110065622-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION FOR SEMICONDUCTOR PROCESSING | TNNI3K, TNK1, NIT2 | LMNA 3059/4885MAPK1 1065/4885CES2 3669/4885 |
| US-20110033507-A1 | Polypeptides KXK and Their Use | NPR3, NGLY1, NPR1 | LMNA 828/4885MAPK1 3481/4885CES2 4322/4885 |
| US-20120076842-A1 | COSMETIC USE OF TYR-ARG DIPEPTIDE TO COMBAT CUTANEOUS SAGGING | ARGLU1, CUTA, ARG1 | LMNA 3387/4885MAPK1 2953/4885CES2 2466/4885 |
| US-20110045036-A1 | Cosmetic Compositions Comprising at Least One Peptide with at Least One Immobilized Aromatic Cycle | TYR, XPA, MC1R | LMNA 268/4885MAPK1 2667/4885CES2 2836/4885 |
| US-20110002865-A1 | MOISTURIZING COSMETIC COMPOSITION COMPRISING A COMBINATION OF HOMARINE AND ERYTHRITOL | AQP1, CUTA, AQP3 | LMNA 2297/4885MAPK1 3877/4885CES2 2359/4885 |
| US-20120028916-A1 | COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES | DPM1, MC1R, SLTM | LMNA 1393/4885MAPK1 3655/4885CES2 2268/4885 |
| US-20110027336-A1 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME | LDHA, LDHB, CA1 | LMNA 2203/4885MAPK1 1734/4885CES2 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.