Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hippuric Acid SCHEMBL1609915 | 0.76 | NPC1 (0.49) | GPR139KDM4EEPHX2NPC1RAB9A | |
| Hippuric Acid SCHEMBL2405067 | 0.76 | KDM4E (0.56) | GPR139KDM4ENPC1RAB9ASMN1; SMN2 | |
| Hippuric Acid SCHEMBL3029 | 0.76 | KDM4E (0.56) | GPR139KDM4ENPC1RAB9ASMN1; SMN2 | |
| Methenamine SCHEMBL2233803 | 0.74 | LMNA (0.47) | ALDH1A1SMN1; SMN2KLK7 | |
| SCHEMBL14219258 | 0.73 | GPR139 (0.55) | ALDH1A1GPR139KDM4EEPHX2NPC1 | |
| SCHEMBL10620106 | 0.72 | CTSK (0.48) | ALDH1A1MDM2KDM4EEPHX2SMN1; SMN2 | |
| SCHEMBL18219349 | 0.72 | CTSK (0.48) | ALDH1A1MDM2KDM4EEPHX2SMN1; SMN2 | |
| Hippuric Acid SCHEMBL2464569 | 0.72 | KDM4E (0.56) | GPR139KDM4ERAB9ASMN1; SMN2GAA | |
| SCHEMBL5655365 | 0.70 | PRSS1 (0.68) | ALDH1A1GPR139NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14219779 | 0.70 | GPR139 (0.51) | ALDH1A1GPR139NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351546-B9 | LONG-ACTING INJECTABLE MOXIDECTIN FORMULATIONS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-07-10 | — | — | EP | disclosed |
| US-12018048-B2 | Anthelmintic depsipeptide compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240166653-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-05-23 | — | — | US | disclosed |
| US-20240132525-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2024-04-25 | — | — | US | disclosed |
| US-11964977-B2 | Anthelmintic heterocyclic compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2024-04-23 | — | — | US | disclosed |
| EP-3351546-B1 | LONG-ACTING INJECTABLE MOXIDECTIN FORMULATIONS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-02-14 | — | — | EP | disclosed |
| WO-2023244775-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
| US-11827657-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-11-28 | — | — | US | disclosed |
| EP-4262789-A1 | PARASITICIDAL COLLAR COMPRISING ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Vetmedica GmbH (DE) | 2023-10-25 | — | — | EP | disclosed |
| EP-4263559-A1 | BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20100125097-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | MERIAL, INC. | 2010-05-20 | — | — | US | disclosed |
| WO-2010056999-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL- 2 -YL CYANOETHYLAMINO PARACITICIDAL COMPOUNDS | MERIAL LIMITED (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100125089-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL, INC. | 2010-05-20 | — | — | US | disclosed |
| WO-2010048191-A1 | THIOAMIDE COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2010-04-29 | — | — | WO | disclosed |
| EP-2155699-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | Merial Limited (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-2035390-A2 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | Aventis Agriculture (FR) | 2009-03-18 | — | — | EP | disclosed |
| US-20080312272-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL, INC. | 2008-12-18 | — | — | US | disclosed |
| WO-2008144275-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2008-11-27 | — | — | WO | disclosed |
| US-20080031902-A1 | 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | MERIAL, INC. | 2008-02-07 | — | — | US | disclosed |
| WO-2008005489-A2 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827657-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | JAK3, JAK1, JAK2 | ALDH1A1 3977/4885MDM2 3176/4885GPR139 4035/4885 |
| US-12018048-B2 | Anthelmintic depsipeptide compounds | VIP, DNPEP, DPEP1 | ALDH1A1 2924/4885MDM2 3937/4885GPR139 1993/4885 |
| US-11964977-B2 | Anthelmintic heterocyclic compounds | AADAC, HNMT, HRH4 | ALDH1A1 651/4885MDM2 4656/4885GPR139 3923/4885 |
| US-20080031902-A1 | 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | CBR3, CBR1, NR5A2 | ALDH1A1 3749/4885MDM2 4754/4885GPR139 342/4885 |
| US-20080312272-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | CYP4X1, CBR3, TYR | ALDH1A1 1677/4885MDM2 2252/4885GPR139 2712/4885 |
| US-20100125089-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | CYP4B1, NPY4R, CYP4X1 | ALDH1A1 1144/4885MDM2 1906/4885GPR139 2071/4885 |
| US-20240166653-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | AADAC, HNMT, HRH4 | ALDH1A1 651/4885MDM2 4656/4885GPR139 3923/4885 |
| US-20100125097-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | TYR, CAT, NAT1 | ALDH1A1 766/4885MDM2 1558/4885GPR139 4834/4885 |
| US-20240132525-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | JAK2, JAK1, JAK3 | ALDH1A1 3629/4885MDM2 2605/4885GPR139 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.