Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11769668 | 0.90 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPTTSHRALOX15 | |
| SCHEMBL7632848 | 0.82 | TSHR (0.44) | ALDH1A1TDP1MAPTTSHRPOLB | |
| SCHEMBL2234042 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TDP1MAPTTSHRALOX15 | |
| SCHEMBL30352396 | 0.77 | KDM4E (0.41) | ALDH1A1TDP1MAPTTSHRPOLB | |
| SCHEMBL9271980 | 0.77 | MAPT (0.47) | ALDH1A1TDP1MAPTTSHRPOLB | |
| SCHEMBL327401 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTTSHRALOX15HSD17B10 | |
| SCHEMBL3092932 | 0.72 | MAPT (0.47) | ALDH1A1TDP1MAPTTSHRPOLB | |
| SCHEMBL5434824 | 0.72 | MAPT (0.44) | ALDH1A1MAPTTSHRPOLBKDM4E | |
| SCHEMBL6694368 | 0.72 | NPC1 (0.44) | ALDH1A1TDP1MAPTTSHRPOLB | |
| SCHEMBL2564135 | 0.72 | MAPT (0.47) | ALDH1A1TDP1MAPTTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981990-B2 | Synthesis of a liquid polymer and a functionalized polymer | BRIDGESTONE CORPORATION (JP) | 2011-07-19 | — | — | US | claimed |
| JP-2010538109-A | — | — | 2010-12-09 | — | — | JP | claimed |
| EP-2193150-A2 | SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER | Bridgestone Corporation (JP) | 2010-06-09 | — | — | EP | claimed |
| WO-2009032154-A2 | SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER | BRIDGESTONE CORPORATION (JP) | 2009-03-12 | — | — | WO | claimed |
| US-20090062451-A1 | SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER | BRIDGESTONE CORPORATION (JP) | 2009-03-05 | — | — | US | claimed |
| EP-2193150-B1 | SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER | BRIDGESTONE CORP (JP) | 2020-09-23 | — | — | EP | disclosed |
| EP-2193150-B1 | SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER | BRIDGESTONE CORP (JP) | 2020-09-23 | — | — | EP | disclosed |
| EP-2266993-B1 | The use of sulfur containing initiators for anionic polymerization of monomers | BRIDGESTONE CORP (JP) | 2017-06-14 | — | — | EP | disclosed |
| EP-2658898-B1 | COUPLED POLYMERS AND METHODS FOR MAKING SAME | BRIDGESTONE CORP (JP) | 2016-10-12 | — | — | EP | disclosed |
| US-9441097-B2 | Rubber composition and tire produced by using the same | BRIDGESTONE CORPORATION (JP) | 2016-09-13 | — | — | US | disclosed |
| US-9441097-B2 | Rubber composition and tire produced by using the same | BRIDGESTONE CORPORATION (JP) | 2016-09-13 | — | — | US | disclosed |
| US-9441097-B2 | Rubber composition and tire produced by using the same | BRIDGESTONE CORPORATION (JP) | 2016-09-13 | — | — | US | disclosed |
| US-7153919-B2 | Use of sulfur containing initiators for anionic polymerization of monomers | BRIDGESTONE CORPORATION (JP) | 2006-12-26 | — | — | US | disclosed |
| WO-2006047328-A1 | FUNCTIONALIZED POLYMER WITH LINKING GROUP | BRIDGESTONE CORPORATION (JP) | 2006-05-04 | — | — | WO | disclosed |
| US-20060030657-A1 | Use of sulfur containing initiators for anionic polymerization of monomers | BRIDGESTONE CORPORATION (JP) | 2006-02-09 | — | — | US | disclosed |
| EP-1565476-A2 | THE USE OF SULFUR CONTAINING INITIATORS FOR ANIONIC POLYMERIZATION OF MONOMERS | Bridgestone Corporation (JP) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004041870-A2 | THE USE OF SULFUR CONTAINING INITIATORS FOR ANIONIC POLYMERIZATION OF MONOMERS | BRIDGESTONE CORPORATION (JP) | 2004-05-21 | — | — | WO | disclosed |
| US-4127588-A | Sulphur containing derivatives | HOFFMANN-LA ROCHE INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4073797-A | CORONARY DILATOR | HOFFMANN-LA ROCHE INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4003914-A | DITHIANE AND DISULFONE CORONARY DILATING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062451-A1 | SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER | FGB, FIP1L1, PUF60 | ALDH1A1 1640/4885TDP1 3211/4885MAPT 2672/4885 |
| US-20060030657-A1 | Use of sulfur containing initiators for anionic polymerization of monomers | TST, ESD, VCL | ALDH1A1 3070/4885TDP1 934/4885MAPT 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.