Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22340458 | 0.88 | PTGES (0.45) | PTGESTAS2R14CNR2 | |
| SCHEMBL29335919 | 0.88 | PTGES (0.45) | PTGESTAS2R14CNR2 | |
| SCHEMBL20870805 | 0.88 | PTGES (0.45) | PTGESTAS2R14CNR2 | |
| SCHEMBL20870834 | 0.88 | PTGES (0.45) | PTGESTAS2R14CNR2 | |
| SCHEMBL20871141 | 0.87 | PTGES (0.46) | PTGESTAS2R14BCHERORC | |
| SCHEMBL29334346 | 0.83 | PTGES (0.47) | PTGESTAS2R14BCHERORC | |
| SCHEMBL20870807 | 0.81 | DRD2 (0.47) | DRD2CNR2 | |
| SCHEMBL22340723 | 0.80 | DRD2 (0.48) | DRD2CNR2 | |
| SCHEMBL22340915 | 0.80 | DRD2 (0.48) | DRD2CNR2 | |
| SCHEMBL22340459 | 0.80 | DRD2 (0.48) | DRD2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | Universite Paris-Saclay (FR) | 2021-06-15 | — | — | US | disclosed |
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | Universite Paris-Saclay (FR) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | ADH1C, ADH1A, ADH5 | DRD2 58/4885PTGES 2690/4885TAS2R14 1287/4885 |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | ADH1C, PNMT, ADH1A | DRD2 91/4885PTGES 2575/4885TAS2R14 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.