SCHEMBL22344835

SCHEMBL22344835

Nc1cccc(N)c1-c1nc(Cl)nc(Cl)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
HPGD P15428 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 2/20 0.39
GLA P06280 1/20 0.39
TSHR P16473 5/20 0.37
NR4A2 P43354 1/20 0.37
ALOX15 P16050 2/20 0.36
CYP3A4 P08684 5/20 0.35
HSD17B10 Q99714 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
KEAP1 Q14145 1/20 0.34
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PIK3CA P42336 1/20 0.33
PTPRC P08575 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10343282 0.79 TTR (0.47) ALDH1A1HPGDKDM4ETSHRALOX15
SCHEMBL1136969 0.76 ALDH1A1 (0.50) ALDH1A1HPGDSMN1; SMN2LMNAKDM4E
SCHEMBL2508698 0.73 HSP90AA1 (0.44) ALDH1A1HPGDSMN1; SMN2LMNAKDM4E
SCHEMBL10203915 0.73 RAB9A (0.44) ALDH1A1SMN1; SMN2LMNAKDM4ETSHR
SCHEMBL17156499 0.70 HRH4 (0.50) ALDH1A1HPGDSMN1; SMN2LMNAKDM4E
SCHEMBL22232393 0.69 ADRB2 (0.41) ALDH1A1HPGDSMN1; SMN2LMNAKDM4E
SCHEMBL24497130 0.68 HPGD (0.45) ALDH1A1HPGDSMN1; SMN2LMNAKDM4E
SCHEMBL413486 0.68 PTGES (0.43) ALDH1A1SMN1; SMN2LMNAKDM4ETSHR
SCHEMBL5031305 0.68 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2LMNAKDM4ETSHR
SCHEMBL3036922 0.68 CYP3A4 (0.57) ALDH1A1HPGDSMN1; SMN2TSHRNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111065628-B Novel triazine derivative and photosensitive composition comprising the same 株式会社特雷尔 2023-06-02 CN disclosed
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TREEEL CO., LTD (KR) 2020-08-20 US disclosed
CN-111065628-A Novel triazine derivative and photosensitive composition comprising the same 株式会社特雷尔 2020-04-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TYR, CRY2, CRY1 ALDH1A1 468/4885HPGD 2394/4885SMN1; SMN2 4863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.