Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116947 | 0.83 | NR1I2 (0.35) | — | |
| SCHEMBL26137621 | 0.78 | KIF11 (0.34) | CASRKIF11CMKLR1 | |
| SCHEMBL22156297 | 0.78 | GRM4 (0.43) | CASRKIF11CMKLR1 | |
| SCHEMBL20116951 | 0.71 | CMKLR1 (0.35) | CASRCMKLR1 | |
| SCHEMBL22357741 | 0.69 | MPO (0.36) | CASRCMKLR1 | |
| SCHEMBL26721595 | 0.68 | CASR (0.35) | CASRKIF11 | |
| SCHEMBL19543368 | 0.67 | KIF11 (0.41) | CASRKIF11 | |
| SCHEMBL22358065 | 0.65 | LMNA (0.36) | KIF11 | |
| SCHEMBL12611289 | 0.63 | KIF11 (0.41) | KIF11 | |
| SCHEMBL21179014 | 0.63 | RET (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | CASR 3724/4885KIF11 1969/4885CMKLR1 4657/4885 |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | CASR 3724/4885KIF11 1969/4885CMKLR1 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.