Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15396022 | 0.79 | NPC1 (0.40) | XDHMETAP2SMN1; SMN2MAPTRAB9A | |
| SCHEMBL18829052 | 0.79 | METAP2 (0.38) | XDHMETAP2SMN1; SMN2MAPTRAB9A | |
| SCHEMBL15331765 | 0.76 | MCL1 (0.39) | XDHMETAP2SMN1; SMN2MAPTRAB9A | |
| SCHEMBL5924343 | 0.69 | MAPT (0.47) | XDHMETAP2SMN1; SMN2MAPTRAB9A | |
| SCHEMBL24484639 | 0.69 | RAB9A (0.47) | XDHMETAP2SMN1; SMN2MAPTRAB9A | |
| SCHEMBL27992256 | 0.69 | MCL1 (0.42) | XDHMETAP2SMN1; SMN2MAPTRAB9A | |
| SCHEMBL15396034 | 0.67 | PDGFRB (0.31) | — | |
| SCHEMBL15135573 | 0.66 | LMNA (0.43) | METAP2SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL16428799 | 0.66 | ADRA2A (0.42) | XDHMETAP2SMN1; SMN2MAPTRAB9A | |
| SCHEMBL8744752 | 0.66 | ERBB2 (0.41) | XDHMETAP2SMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699176-A2 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2020-08-26 | — | — | EP | disclosed |