Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744832 | 0.82 | MCL1 (0.42) | ADORA2AADORA1MAPTKMT2ANPSR1 | |
| SCHEMBL8744743 | 0.82 | MCL1 (0.41) | ERBB2METAP2ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL8744742 | 0.82 | CYP11B1 (0.43) | ERBB2METAP2ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL7432291 | 0.81 | ADORA2A (0.41) | ERBB2ADORA2AADORA1SMN1; SMN2MAPT | |
| SCHEMBL8744764 | 0.81 | CTSS (0.48) | METAP2ADORA2AADORA1SMN1; SMN2MAPT | |
| SCHEMBL8744693 | 0.80 | CCNC (0.47) | ADORA2AADORA1MAPTLMNANPC1 | |
| SCHEMBL8744687 | 0.78 | KIF11 (0.47) | — | |
| SCHEMBL8744692 | 0.78 | CYP2A6 (0.43) | METAP2SMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL9876232 | 0.76 | MAPT (0.43) | MAPTKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL8744748 | 0.72 | IDO1 (0.41) | MAPK14SMN1; SMN2MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |