Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932783 | 0.79 | L3MBTL1 (0.66) | TSHRL3MBTL1KDM4EHPGDALDH1A1 | |
| SCHEMBL26812621 | 0.75 | L3MBTL1 (1.00) | TSHRL3MBTL1KDM4EHPGDALDH1A1 | |
| SCHEMBL1122737 | 0.75 | PKM (0.60) | TSHRL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL5936640 | 0.74 | PARP10 (0.60) | TSHRL3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL1123053 | 0.73 | MAPT (0.63) | TSHRL3MBTL1KDM4EHPGDALDH1A1 | |
| SCHEMBL804981 | 0.72 | TSHR (0.61) | TSHRL3MBTL1KDM4EHPGDALDH1A1 | |
| SCHEMBL1123321 | 0.72 | KMT2A (0.57) | TSHRL3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL22372364 | 0.71 | L3MBTL1 (0.47) | TSHRL3MBTL1KDM4EHPGDALDH1A1 | |
| SCHEMBL13896740 | 0.70 | GAA (0.40) | TSHRALDH1A1KMT2AGAARECQL | |
| SCHEMBL11208809 | 0.70 | PDE3B (0.48) | ALDH1A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |