Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 8/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19506154 | 0.91 | CTSS (0.37) | CTSSCTSKTLR2CAPN1PLK1 | |
| SCHEMBL16791114 | 0.79 | PLK1 (0.42) | TLR2PLK1MEN1KMT2A | |
| SCHEMBL20998108 | 0.77 | CTSK (0.41) | CTSSCTSKCAPN1PLK1P2RY12 | |
| SCHEMBL19450704 | 0.73 | CAPN1 (0.37) | CTSSCTSKCAPN1PLK1GLP1R | |
| SCHEMBL18291443 | 0.72 | CTSS (0.45) | CTSSCTSKCAPN1PLK1 | |
| SCHEMBL30019872 | 0.71 | NOD1 (0.47) | CAPN1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30019912 | 0.71 | NOD1 (0.47) | TLR2CAPN1MEN1KMT2AALDH1A1 | |
| SCHEMBL19450731 | 0.71 | CTSK (0.39) | CTSSCTSKPLK1P2RY12 | |
| SCHEMBL30565194 | 0.70 | NOD1 (0.40) | CTSSCTSK | |
| SCHEMBL7257742 | 0.70 | L3MBTL1 (0.38) | CTSSCTSKPLK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268885-A1 | Conjugates And Conjugating Reagents | POLYTHERICS LIMITED (GB) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268885-A1 | Conjugates And Conjugating Reagents | ANPEP, NGLY1, PCTP | CTSS 2116/4885CTSK 2525/4885TLR2 3035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.