Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384212 | 0.89 | ACACB (0.36) | CTSSCTSKKMT2AACACBHRH2 | |
| SCHEMBL22384328 | 0.89 | ACACB (0.34) | CTSSCTSKACACBHRH2HRH1 | |
| SCHEMBL16305910 | 0.85 | ITGB3 (0.36) | CTSSCTSKKMT2AACACBHRH2 | |
| SCHEMBL22756197 | 0.85 | ITGB3 (0.36) | CTSSCTSKKMT2AACACBHRH2 | |
| SCHEMBL22384134 | 0.78 | HRH2 (0.44) | HRH2HRH1 | |
| SCHEMBL17532278 | 0.77 | P2RX7 (0.52) | CTSKKMT2AHRH2HRH1MAPK1 | |
| SCHEMBL16295734 | 0.77 | HRH2 (0.46) | HRH2HRH1 | |
| SCHEMBL16295733 | 0.77 | HRH2 (0.46) | HRH2HRH1 | |
| SCHEMBL19485536 | 0.76 | HRH2 (0.42) | HRH2HRH1 | |
| SCHEMBL16305994 | 0.76 | HRH2 (0.48) | HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |