Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 6/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384194 | 0.89 | CTSS (0.36) | ACACBCTSSCTSKMAPK1HRH2 | |
| SCHEMBL17834409 | 0.87 | ACACB (0.33) | ACACBFEN1ALOX5APHRH2HRH1 | |
| SCHEMBL22384132 | 0.87 | ACACB (0.33) | ACACBFEN1ALOX5APHRH2HRH1 | |
| SCHEMBL22384212 | 0.83 | ACACB (0.36) | ACACBCTSSCTSKMAPK1HRH2 | |
| SCHEMBL17834418 | 0.79 | P2RX7 (0.43) | CTSKMAPK1HRH2HRH1P2RX7 | |
| SCHEMBL22384231 | 0.79 | P2RX7 (0.43) | CTSKMAPK1HRH2HRH1P2RX7 | |
| SCHEMBL17834535 | 0.79 | DPP4 (0.41) | ACACBFEN1ALOX5APHRH2HRH1 | |
| SCHEMBL17968892 | 0.78 | PYGL (0.35) | FEN1ALOX5APDPP4HCAR2HPGDS | |
| SCHEMBL17968893 | 0.78 | PYGL (0.35) | FEN1ALOX5APDPP4HCAR2HPGDS | |
| SCHEMBL22384167 | 0.77 | KIFC1 (0.33) | ACACBFEN1ALOX5APHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |