Sugi Predict

Sugi Predict / Compounds / SCHEMBL2238679

SCHEMBL2238679

SCHEMBL2238679

Cc1ccc(-c2c[c]co2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.44
▸ PKM P14618 1/20 0.44
▸ NOTUM Q6P988 1/20 0.35
▸ ACHE P22303 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ ENPP3 O14638 1/20 0.34
▸ ENPP1 P22413 1/20 0.34
▸ RAB9A P51151 4/20 0.34
▸ MAOB P27338 4/20 0.34
▸ NPC1 O15118 3/20 0.34
▸ CASP3 P42574 1/20 0.34
▸ SENP8 Q96LD8 1/20 0.34
▸ SENP7 Q9BQF6 1/20 0.34
▸ SENP6 Q9GZR1 1/20 0.34
▸ SMN1; SMN2 Q16637 4/20 0.33
▸ KDM4E B2RXH2 3/20 0.33
▸ ALDH1A1 P00352 3/20 0.33
▸ HPGD P15428 3/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL3763584 0.66 ACHE (0.67) LMNAACHETDP1ENPP3ENPP1
Water SCHEMBL3680095 0.66 ACHE (0.67) LMNAACHETDP1ENPP3ENPP1
SCHEMBL4343079 0.66 NQO2 (0.53) LMNAPKMACHETDP1RAB9A
SCHEMBL14541695 0.64 NQO2 (0.52) LMNAPKMACHETDP1RAB9A
SCHEMBL8922910 0.64 LMNA (0.47) LMNAPKMNOTUMACHETDP1
SCHEMBL7333592 0.64 LMNA (0.47) LMNAPKMNOTUMACHETDP1
SCHEMBL3695550 0.64 TAAR1 (0.61) LMNAPKMTDP1RAB9ANPC1
SCHEMBL18661495 0.63 ACHE (0.73) LMNAACHETDP1ENPP3ENPP1
SCHEMBL3287696 0.63 ACHE (0.73) LMNAACHETDP1ENPP3ENPP1
SCHEMBL197731 0.63 ACHE (0.73) LMNAACHETDP1ENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115315451-B Catalyst for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer using catalyst for olefin polymerization 日本聚丙烯株式会社 2023-12-01 — — CN disclosed
US-20230331881-A1 PRODUCTION OF POLYPROPYLENE WITH LOW VOLATILES BOREALIS AG (AT) 2023-10-19 — — US disclosed
US-20230142911-A1 OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMERIZATION CATALYST PRODUCTION METHOD, AND OLEFIN POLYMER PRODUCTION METHOD USING THE OLEFIN POLYMERIZATION CATALYST JAPAN POLYPROPYLENE CORPORATION (JP) 2023-05-11 — — US disclosed
CN-115702174-A Production of polypropylene with low volatiles 博里利斯股份公司 2023-02-14 — — CN disclosed
EP-4105246-A1 CATALYST FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER USING SAID CATALYST FOR OLEFIN POLYMERIZATION Japan Polypropylene Corporation (JP) 2022-12-21 — — EP disclosed
US-20220396695-A1 HETEROPHASIC PROPYLENE ETHYLENE COPOLYMER COMPOSITION WITH DESIRABLE BALANCE OF MECHANICAL PROPERTIES BOREALIS AG (AT) 2022-12-15 — — US disclosed
CN-115315451-A Olefin polymerization catalyst, method for producing olefin polymerization catalyst, and method for producing olefin polymer using olefin polymerization catalyst 日本聚丙烯株式会社 2022-11-08 — — CN disclosed
CN-114616280-A Heterophasic propylene ethylene copolymer compositions having a desirable balance of mechanical properties 北欧化工公司 2022-06-10 — — CN disclosed
WO-2021254938-A1 PRODUCTION OF POLYPROPYLENE WITH LOW VOLATILES BOREALIS AG (AT) 2021-12-23 — — WO disclosed
EP-3925986-A1 PRODUCTION OF POLYPROPYLENE WITH LOW VOLATILES Borealis AG (AT) 2021-12-22 — — EP disclosed
EP-3121187-A1 METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2017-01-25 — — EP disclosed
CN-106132975-A metallocene complex and process for producing olefin polymer 日本聚丙烯株式会社 2016-11-16 — — CN disclosed
EP-2915816-B1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORP (JP) 2016-05-25 — — EP disclosed
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORPORATION (JP) 2015-09-24 — — US disclosed
EP-2915816-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD Japan Polypropylene Corporation (JP) 2015-09-09 — — EP disclosed
CN-104781270-A Metallocene complexes and olefin polymerization process JAPAN POLYPROPYLENE CORP 2015-07-15 — — CN disclosed
US-8461365-B2 Metallocene complex and polymerization method of olefin JAPAN POLYPROPYLENE CORPORATION (JP) 2013-06-11 — — US disclosed
CN-102245620-A Metallocene complex and method for polymerizing olefin JAPAN POLYPROPYLENE CORP 2011-11-16 — — CN disclosed
US-20110230622-A1 METALLOCENE COMPLEX AND POLYMERIZATION METHOD OF OLEFIN JAPAN POLYPROPYLENE CORPORATION (JP) 2011-09-22 — — US disclosed
EP-2360163-A1 METALLOCENE COMPLEX AND METHOD FOR POLYMERIZING OLEFIN Japan Polypropylene Corporation (JP) 2011-08-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230622-A1 METALLOCENE COMPLEX AND POLYMERIZATION METHOD OF OLEFIN ALOX12, ALOX15, ALOX15B LMNA 3617/4885PKM 3290/4885NOTUM 434/4885
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD POR, OPRM1, ALOX12 LMNA 3913/4885PKM 1485/4885NOTUM 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.