Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22545497 | 0.86 | ALDH1A1 (0.33) | ROCK1CYP3A4ALDH1A1LMNACXCR2 | |
| SCHEMBL16113392 | 0.83 | UCHL1 (0.33) | ROCK1ALDH1A1LMNACXCR2UCHL1 | |
| SCHEMBL16113731 | 0.81 | UCHL1 (0.34) | ROCK1ALDH1A1UCHL1KDM4EGAA | |
| SCHEMBL12470442 | 0.80 | PKM (0.34) | ROCK1ALDH1A1LMNACXCR2UCHL1 | |
| SCHEMBL25287007 | 0.80 | EGFR (0.41) | ALDH1A1LMNACXCR2UCHL1KDM4E | |
| SCHEMBL24468125 | 0.80 | CFTR (0.40) | ALDH1A1UCHL1KDM4EGAAMAPT | |
| SCHEMBL31394282 | 0.79 | KDM4E (0.35) | ROCK1ALDH1A1LMNACXCR2UCHL1 | |
| SCHEMBL12470552 | 0.78 | UCHL1 (0.34) | ROCK1ALDH1A1UCHL1KDM4EGAA | |
| SCHEMBL23291792 | 0.77 | GAA (0.38) | ALDH1A1LMNAUCHL1GAAMAPT | |
| SCHEMBL18107886 | 0.77 | CA12 (0.37) | ALDH1A1LMNAUCHL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122226-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2025-04-17 | — | — | US | disclosed |
| US-12227528-B2 | Glucose-sensitive albumin-binding derivatives | NOVO NORDISK A/S (DK) | 2025-02-18 | — | — | US | disclosed |
| CN-117624207-A | Glucose-sensitive albumin binding derivatives | 诺和诺德股份有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-111315751-B | Glucose-sensitive albumin binding derivatives | 诺和诺德股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-20230331745-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2023-10-19 | — | — | US | disclosed |
| US-11767332-B2 | Glucose-sensitive albumin-binding derivatives | NOVO NORDISK A/S (DK) | 2023-09-26 | — | — | US | disclosed |
| EP-4227313-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | Novo Nordisk A/S (DK) | 2023-08-16 | — | — | EP | disclosed |
| EP-3707145-B1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2023-06-21 | — | — | EP | disclosed |
| US-20220081451-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2022-03-17 | — | — | US | disclosed |
| US-11186595-B2 | Glucose-sensitive albumin-binding derivatives | NOVO NORDISK A/S (DK) | 2021-11-30 | — | — | US | disclosed |
| US-20200325160-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK A/S (DK) | 2020-10-15 | — | — | US | disclosed |
| EP-3707145-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | Novo Nordisk A/S (DK) | 2020-09-16 | — | — | EP | disclosed |
| CN-111315751-A | Glucose-sensitive albumin binding derivatives | 诺沃挪第克公司 | 2020-06-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12227528-B2 | Glucose-sensitive albumin-binding derivatives | ALB, DBI, FABP4 | ROCK1 4574/4885CYP3A4 1793/4885ALDH1A1 1240/4885 |
| US-20230331745-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | ALB, DBI, FABP4 | ROCK1 4574/4885CYP3A4 1793/4885ALDH1A1 1240/4885 |
| US-11767332-B2 | Glucose-sensitive albumin-binding derivatives | ALB, DBI, FABP4 | ROCK1 4574/4885CYP3A4 1793/4885ALDH1A1 1240/4885 |
| US-20220081451-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | ALB, DBI, FABP4 | ROCK1 4574/4885CYP3A4 1793/4885ALDH1A1 1240/4885 |
| US-20250122226-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | ALB, DBI, FABP4 | ROCK1 4574/4885CYP3A4 1793/4885ALDH1A1 1240/4885 |
| US-11186595-B2 | Glucose-sensitive albumin-binding derivatives | ALB, GPR119, MLX | ROCK1 3522/4885CYP3A4 990/4885ALDH1A1 456/4885 |
| US-20200325160-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | ALB, GPR119, MLX | ROCK1 3522/4885CYP3A4 990/4885ALDH1A1 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.