Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15895098 | 0.85 | RIPK1 (0.42) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL23175981 | 0.85 | RIPK1 (0.42) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL23175980 | 0.83 | ALDH1A1 (0.40) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL23613007 | 0.80 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL18287166 | 0.77 | ALDH1A1 (0.41) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL7230655 | 0.75 | ALDH1A1 (0.46) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL24235744 | 0.72 | POLB (0.51) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL292612 | 0.71 | — | — | |
| SCHEMBL2823638 | 0.71 | ALDH1A1 (0.48) | ALDH1A1POLBHPGDKMT2ANPC1 | |
| SCHEMBL26504336 | 0.69 | TAS1R3 (0.46) | TAS1R3TAS1R1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11471411-B2 | Polymer nanodiscs for biotechnology and medical applications | TEXAS TECH UNIVERSITY SYSTEM (US) | 2022-10-18 | — | — | US | disclosed |
| US-20200281855-A1 | Polymer Nanodiscs for Biotechnology and Medical Applications | TEXAS TECH UNIVERSITY SYSTEM | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11471411-B2 | Polymer nanodiscs for biotechnology and medical applications | SDCBP, NUP210, LNPK | ALDH1A1 4809/4885POLB 3980/4885HPGD 3861/4885 |
| US-20200281855-A1 | Polymer Nanodiscs for Biotechnology and Medical Applications | SDCBP, NUP210, LNPK | ALDH1A1 4809/4885POLB 3980/4885HPGD 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.