Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23175981 | 0.86 | RIPK1 (0.42) | ALDH1A1KMT2APOLBHPGDMEN1 | |
| SCHEMBL15895098 | 0.86 | RIPK1 (0.42) | ALDH1A1KMT2APOLBHPGDMEN1 | |
| SCHEMBL15895091 | 0.86 | MMP1 (0.42) | ALDH1A1KMT2ATDP1MEN1RAB9A | |
| SCHEMBL22403767 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KMT2APOLBHPGDMEN1 | |
| SCHEMBL23613007 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2APOLBHPGDMEN1 | |
| SCHEMBL18287166 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2APOLBHPGDMEN1 | |
| SCHEMBL5901349 | 0.77 | MME (0.41) | ALDH1A1KMT2ATDP1MEN1RAB9A | |
| SCHEMBL7230655 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2APOLBHPGDRAB9A | |
| SCHEMBL24176580 | 0.76 | TDP1 (0.39) | ALDH1A1KMT2ATDP1MEN1RAB9A | |
| SCHEMBL2823638 | 0.72 | ALDH1A1 (0.48) | ALDH1A1KMT2ATDP1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094950-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094950-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | CSNK1A1, CSNK1E, CSNK1G3 | ALDH1A1 4302/4885KMT2A 1893/4885TDP1 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.