Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28260452 | 0.90 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL8986919 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL28259098 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL5842582 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL9821491 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL2932844 | 0.82 | GAA (0.50) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL28866677 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1MAPTLMNATDP1MEN1 | |
| SCHEMBL6423919 | 0.80 | CA1 (0.67) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL28198 | 0.80 | CA1 (0.67) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL5843026 | 0.79 | POLB (0.45) | ALDH1A1MAPTLMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129782-B2 | Derivatives of PPD useful for coloring hair and skin | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-09-28 | — | — | US | disclosed |
| US-20210179545-A1 | COMPOSITIONS OF OLIGOANILINES AND METHODS OF MAKING AND USING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-06-17 | — | — | US | disclosed |
| US-20200390670-A1 | DERIVATIVES OF PPD USEFUL FOR COLORING HAIR AND SKIN | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2020-12-17 | — | — | US | disclosed |
| US-20200290954-A1 | COMPOSITIONS OF OLIGOANILINES AND METHODS OF MAKING AND USING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179545-A1 | COMPOSITIONS OF OLIGOANILINES AND METHODS OF MAKING AND USING | AOX1, LPO, POLI | ALDH1A1 1812/4885MAPT 4458/4885LMNA 1888/4885 |
| US-20200290954-A1 | COMPOSITIONS OF OLIGOANILINES AND METHODS OF MAKING AND USING | AOX1, LPO, POLI | ALDH1A1 1812/4885MAPT 4458/4885LMNA 1888/4885 |
| US-11129782-B2 | Derivatives of PPD useful for coloring hair and skin | TST, SDHB, NDUFS3 | ALDH1A1 672/4885MAPT 2765/4885LMNA 2116/4885 |
| US-20200390670-A1 | DERIVATIVES OF PPD USEFUL FOR COLORING HAIR AND SKIN | TST, SDHB, NDUFS3 | ALDH1A1 672/4885MAPT 2765/4885LMNA 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.