Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656230 | 0.87 | KDM4E (0.31) | KDM4EGAAMAPT | |
| SCHEMBL10437514 | 0.84 | ALDH1A1 (0.37) | KDM4EGAAMAPTALDH1A1TSHR | |
| SCHEMBL8655726 | 0.84 | KDM4E (0.30) | KDM4EGAAMAPT | |
| SCHEMBL6841722 | 0.84 | CHEK1 (0.34) | KDM4EGAAMAPTALDH1A1TSHR | |
| SCHEMBL3087872 | 0.81 | KDM4E (0.31) | KDM4EALDH1A1 | |
| SCHEMBL5563019 | 0.79 | CYP2A6 (0.34) | GAAALDH1A1 | |
| SCHEMBL7827444 | 0.74 | CYP3A4 (0.39) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL127066 | 0.71 | — | — | |
| SCHEMBL638648 | 0.70 | NCF1 (0.36) | KDM4EGAAMAPT | |
| SCHEMBL28053574 | 0.69 | CHEK1 (0.31) | CHEK1NEK2LIMK1DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024060641-A1 | CYCLOTRIARYLPHOSPHINE, METHOD FOR PREPARING SAME, AND USE THEREOF | 东莞市均成高新材料有限公司 | 2024-03-28 | — | — | WO | claimed |
| US-11787827-B2 | Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions | DONGGUAN STEPHEN CATALYST CO., LTD. (CN) | 2023-10-17 | — | — | US | claimed |
| US-20210147452-A1 | TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS | DONGGUAN STEPHEN CATALYST CO., LTD. (CN) | 2021-05-20 | — | — | US | claimed |
| EP-3766891-A1 | TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS | Dongguan Stephen Catalyst Co., Ltd. (CN) | 2021-01-20 | — | — | EP | claimed |
| WO-2019170163-A1 | TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS | 东莞市均成高新材料有限公司 | 2019-09-12 | — | — | WO | claimed |
| EP-3428202-A1 | PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM | ExxonMobil Chemical Patents Inc. (US) | 2019-01-16 | — | — | EP | claimed |
| EP-2536735-B1 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-08-01 | — | — | EP | claimed |
| US-9611348-B2 | Process of producing polyolefins using metallocene polymerization catalysts and copolymers therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-04-04 | — | — | US | claimed |
| EP-2984111-A1 | PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM | ExxonMobil Chemical Patents Inc. (US) | 2016-02-17 | — | — | EP | claimed |
| US-8975259-B2 | Compositions and methods for inhibiting G protein signaling | UNIVERSITY OF ROCHESTER (US) | 2015-03-10 | — | — | US | claimed |
| US-20140316085-A1 | Process of Producing Polyolefins Using Metallocene Polymerization Catalysts and Copolymers Therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2014-10-23 | — | — | US | claimed |
| WO-2014169017-A1 | PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-10-16 | — | — | WO | claimed |
| US-20100130505-A1 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2010-05-27 | — | — | US | claimed |
| EP-2147310-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | University of Rochester (US) | 2010-01-27 | — | — | EP | claimed |
| WO-2009020677-A9 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIV ROCHESTER (US) | 2009-04-16 | — | — | WO | claimed |
| WO-2009020677-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2009-02-12 | — | — | WO | claimed |
| US-11787827-B2 | Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions | DONGGUAN STEPHEN CATALYST CO., LTD. (CN) | 2023-10-17 | — | — | US | disclosed |
| US-11548984-B2 | Light- or heat-curing method and curable resin composition | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2023-01-10 | — | — | US | disclosed |
| US-20030069276-A1 | Amino piperidine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | US | disclosed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787827-B2 | Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions | WEE1, WEE2, NOTUM | KDM4E 3581/4885GAA 3099/4885MAPT 4321/4885 |
| US-20030069276-A1 | Amino piperidine derivatives | CCR5, CCR2, CXCR4 | KDM4E 784/4885GAA 4371/4885MAPT 4405/4885 |
| US-20100130505-A1 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | GNAI1, GNAI3, GNAI2 | KDM4E 4575/4885GAA 1115/4885MAPT 3637/4885 |
| US-20210147452-A1 | TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS | WEE1, WEE2, NOTUM | KDM4E 3652/4885GAA 3048/4885MAPT 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.