Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613655 | 0.83 | KMT2A (0.61) | PPARGPPARALTA4HKMT2AALDH1A1 | |
| SCHEMBL18274704 | 0.82 | TAAR1 (0.52) | KMT2AALDH1A1THRB | |
| SCHEMBL14416710 | 0.82 | RAB9A (0.50) | PPARGPPARAKMT2AALDH1A1LMNA | |
| SCHEMBL23799441 | 0.80 | KMT2A (0.51) | PPARGPPARALTA4HKMT2AALDH1A1 | |
| SCHEMBL16281795 | 0.80 | PPARG (0.44) | PPARGPPARALTA4HKMT2AALDH1A1 | |
| SCHEMBL170186 | 0.80 | KMT2A (0.61) | PPARGPPARALTA4HKMT2AALDH1A1 | |
| SCHEMBL11351213 | 0.79 | KMT2A (0.40) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL343571 | 0.79 | THRB (0.60) | PPARGPPARAKMT2AALDH1A1LMNA | |
| SCHEMBL11151702 | 0.79 | KMT2A (0.45) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL13650268 | 0.79 | MEN1 (0.48) | PPARGPPARALTA4HKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857635-B2 | Linker compound, polyethylene glycol-linker conjugate and derivative thereof and polyethylene glycol-linker-drug conjugate | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2024-01-02 | — | — | US | disclosed |
| US-20200289655-A1 | Linker Compound, Polyethylene Glycol-Linker Conjugate and Derivative Thereof and Polyethylene Glycol-Linker-Drug Conjugate | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200289655-A1 | Linker Compound, Polyethylene Glycol-Linker Conjugate and Derivative Thereof and Polyethylene Glycol-Linker-Drug Conjugate | DCLRE1A, LANCL2, SI | PPARG 2783/4885PPARA 2376/4885LTA4H 1075/4885 |
| US-11857635-B2 | Linker compound, polyethylene glycol-linker conjugate and derivative thereof and polyethylene glycol-linker-drug conjugate | DCLRE1A, LANCL2, SI | PPARG 2783/4885PPARA 2376/4885LTA4H 1075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.