Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22433752 | 0.81 | FADS1 (0.35) | — | |
| SCHEMBL22433986 | 0.76 | IDH1 (0.34) | IDH1 | |
| SCHEMBL22434262 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL22147295 | 0.59 | HTR2A (0.46) | SMN1; SMN2 | |
| SCHEMBL25692383 | 0.59 | ALDH1A1 (0.39) | TSHR | |
| SCHEMBL26359709 | 0.58 | L3MBTL1 (0.38) | TSHRSMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL20706111 | 0.57 | ADORA2A (0.46) | TSHRADORA2AADORA1 | |
| SCHEMBL17995350 | 0.57 | ADORA2A (0.46) | TSHRADORA2AADORA1 | |
| SCHEMBL17952699 | 0.57 | ADORA2A (0.46) | TSHRADORA2AADORA1 | |
| SCHEMBL25823024 | 0.57 | L3MBTL1 (0.49) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200291291-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291291-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TST, MT-ND5, MT-ND4L | IDH1 248/4885GBA1 4357/4885TSHR 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.