Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22434262 | 0.87 | ALDH1A1 (0.33) | LMNA | |
| SCHEMBL22433769 | 0.81 | IDH1 (0.38) | — | |
| SCHEMBL22147295 | 0.78 | HTR2A (0.46) | FADS1HTR2ALMNARAB9ANFKB1 | |
| SCHEMBL22433622 | 0.71 | PBRM1 (0.30) | — | |
| SCHEMBL22433750 | 0.68 | — | — | |
| SCHEMBL23300515 | 0.66 | MTNR1A (0.41) | FADS1 | |
| SCHEMBL31300377 | 0.61 | FADS1 (0.69) | FADS1LMNA | |
| SCHEMBL9541314 | 0.61 | FADS1 (0.69) | FADS1LMNA | |
| SCHEMBL30223619 | 0.60 | PNMT (0.41) | HTR2ADRD2LMNARAB9A | |
| SCHEMBL22433753 | 0.59 | TNKS2 (0.33) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200291291-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291291-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TST, MT-ND5, MT-ND4L | FADS1 4078/4885HTR2A 4452/4885HTR1A 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.